pd 98059 has been researched along with Nasopharyngeal Carcinoma in 3 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Nasopharyngeal Carcinoma: A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. It is most prevalent in Southeast Asian populations and is associated with EPSTEIN-BARR VIRUS INFECTIONS. Somatic mutations associated with this cancer have been identified in NPCR, BAP1, UBAP1, ERBB2, ERBB3, MLL2, PIK3CA, KRAS, NRAS, and ARID1A genes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Curcumin, one of the main bioactive components extracted from a traditional Chinese medicinal herb, exhibits potent anticancer activity against many types of cancer cells including nasopharyngeal carcinoma (NPC)." | 7.80 | Extracellular signal-regulated kinase signaling-mediated induction and interaction of FOXO3a and p53 contribute to the inhibition of nasopharyngeal carcinoma cell growth by curcumin. ( Hahn, SS; Tang, G; Tang, Q; Wu, J; Wu, Y; Zhao, S; Zheng, F, 2014) |
| " Wogonin, a flavonoid compound derived from the traditional Chinese medicine of Huang-Qin, has anticancer activity in many cancer cells including human nasopharyngeal carcinoma (NPC)." | 7.78 | Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells. ( Chen, YW; Chow, SE; Huang, YK; Liang, CA; Wang, JS, 2012) |
| "Curcumin, one of the main bioactive components extracted from a traditional Chinese medicinal herb, exhibits potent anticancer activity against many types of cancer cells including nasopharyngeal carcinoma (NPC)." | 3.80 | Extracellular signal-regulated kinase signaling-mediated induction and interaction of FOXO3a and p53 contribute to the inhibition of nasopharyngeal carcinoma cell growth by curcumin. ( Hahn, SS; Tang, G; Tang, Q; Wu, J; Wu, Y; Zhao, S; Zheng, F, 2014) |
| " Wogonin, a flavonoid compound derived from the traditional Chinese medicine of Huang-Qin, has anticancer activity in many cancer cells including human nasopharyngeal carcinoma (NPC)." | 3.78 | Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells. ( Chen, YW; Chow, SE; Huang, YK; Liang, CA; Wang, JS, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, J | 1 |
| Tang, Q | 1 |
| Zhao, S | 1 |
| Zheng, F | 1 |
| Wu, Y | 1 |
| Tang, G | 1 |
| Hahn, SS | 1 |
| Liu, H | 1 |
| Duan, Z | 1 |
| Zheng, H | 1 |
| Hu, D | 1 |
| Li, M | 1 |
| Tao, Y | 1 |
| Bode, AM | 1 |
| Dong, Z | 1 |
| Cao, Y | 1 |
| Chow, SE | 1 |
| Chen, YW | 1 |
| Liang, CA | 1 |
| Huang, YK | 1 |
| Wang, JS | 1 |
3 other studies available for pd 98059 and Nasopharyngeal Carcinoma
| Article | Year |
|---|---|
Extracellular signal-regulated kinase signaling-mediated induction and interaction of FOXO3a and p53 contribute to the inhibition of nasopharyngeal carcinoma cell growth by curcumin.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Curcumin; Dose-Re | 2014 |
EBV-encoded LMP1 upregulates Igκ 3'enhancer activity and Igκ expression in nasopharyngeal cancer cells by activating the Ets-1 through ERKs signaling.
Topics: Binding Sites; Carcinoma; Cell Line, Tumor; DNA Mutational Analysis; Enzyme Inhibitors; Extracellula | 2012 |
Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells.
Topics: Adenine; Apoptosis; Autophagy; Carcinoma; Cell Line, Tumor; Drugs, Chinese Herbal; Extracellular Sig | 2012 |