pd 98059 has been researched along with MEA 2a in 1 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moreover, we show that the RET-MEN2A-mediated survival depends on signals transduced by the phosphoinositide 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) cascades." | 1.31 | Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival. ( Bellacosa, A; Billaud, M; Carlomagno, F; Castellone, MD; De Vita, G; Fusco, A; Melillo, RM; Santoro, M; Tsichlis, PN; Visconti, R, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Vita, G | 1 |
| Melillo, RM | 1 |
| Carlomagno, F | 1 |
| Visconti, R | 1 |
| Castellone, MD | 1 |
| Bellacosa, A | 1 |
| Billaud, M | 1 |
| Fusco, A | 1 |
| Tsichlis, PN | 1 |
| Santoro, M | 1 |
1 other study available for pd 98059 and MEA 2a
| Article | Year |
|---|---|
Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival.
Topics: Animals; Blotting, Western; Cell Survival; Chromones; Culture Media, Serum-Free; DNA Fragmentation; | 2000 |