Page last updated: 2024-11-02

pd 98059 and Liver Diseases, Alcoholic

pd 98059 has been researched along with Liver Diseases, Alcoholic in 2 studies

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.

Liver Diseases, Alcoholic: Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.

Research Excerpts

ExcerptRelevanceReference
"Arachidonic acid treatment increased NADPH oxidase activity."1.38Arachidonic acid stimulates TNFα production in Kupffer cells via a reactive oxygen species-pERK1/2-Egr1-dependent mechanism. ( Cubero, FJ; Nieto, N, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, Y1
Gao, C1
Shi, Y1
Tang, Y1
Liu, L2
Xiong, T1
Du, M1
Xing, M1
Yao, P1
Cubero, FJ1
Nieto, N1

Other Studies

2 other studies available for pd 98059 and Liver Diseases, Alcoholic

ArticleYear
Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway.
    Toxicology and applied pharmacology, 2013, Nov-15, Volume: 273, Issue:1

    Topics: Alanine Transaminase; Animals; Anthracenes; Aspartate Aminotransferases; Carbon Monoxide; Ethanol; F

2013
Arachidonic acid stimulates TNFα production in Kupffer cells via a reactive oxygen species-pERK1/2-Egr1-dependent mechanism.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, Jul-15, Volume: 303, Issue:2

    Topics: Animals; Antioxidants; Arachidonic Acid; Cell Proliferation; Curcumin; Early Growth Response Protein

2012