pd 98059 has been researched along with Hyperpigmentation in 2 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Hyperpigmentation: Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kang, M | 1 |
| Park, SH | 1 |
| Park, SJ | 1 |
| Oh, SW | 1 |
| Yoo, JA | 1 |
| Kwon, K | 1 |
| Kim, J | 1 |
| Yu, E | 1 |
| Cho, JY | 1 |
| Lee, J | 1 |
| Jin, KS | 1 |
| Oh, YN | 1 |
| Hyun, SK | 1 |
| Kwon, HJ | 1 |
| Kim, BW | 1 |
2 other studies available for pd 98059 and Hyperpigmentation
| Article | Year |
|---|---|
p44/42 MAPK signaling is a prime target activated by phenylethyl resorcinol in its anti-melanogenic action.
Topics: Animals; Benzhydryl Compounds; Cells, Cultured; Flavonoids; Gene Expression Regulation; Humans; Hype | 2019 |
Betulinic acid isolated from Vitis amurensis root inhibits 3-isobutyl-1-methylxanthine induced melanogenesis via the regulation of MEK/ERK and PI3K/Akt pathways in B16F10 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Betulinic Acid; Cell Line, Tumor; Cell Survival; Chromones; CR | 2014 |