Page last updated: 2024-11-02

pd 98059 and Hemorrhagic Shock

pd 98059 has been researched along with Hemorrhagic Shock in 2 studies

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.

Research Excerpts

ExcerptRelevanceReference
" We hypothesized that administration of a specific mitogen-activated protein kinase inhibitor, PD 98059, at the end of resuscitation following severe hemorrhagic shock can reduce the plasma levels of interleukin 6 (IL-6) and hepatocellular damage."3.72The effect of inhibition of a major cell signaling pathway following trauma hemorrhage on hepatic injury and interleukin 6 levels. ( Bland, KI; Chaudry, IH; Jarrar, D; Kuebler, JF; Rue, LW; Song, GY, 2004)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hsu, JT1
Kan, WH1
Hsieh, CH1
Choudhry, MA1
Bland, KI2
Chaudry, IH2
Jarrar, D1
Song, GY1
Kuebler, JF1
Rue, LW1

Other Studies

2 other studies available for pd 98059 and Hemorrhagic Shock

ArticleYear
Role of extracellular signal-regulated protein kinase (ERK) in 17beta-estradiol-mediated attenuation of lung injury after trauma-hemorrhage.
    Surgery, 2009, Volume: 145, Issue:2

    Topics: Acute Lung Injury; Animals; Biomarkers; Chemokine CXCL1; Chemokine CXCL2; Down-Regulation; Estradiol

2009
The effect of inhibition of a major cell signaling pathway following trauma hemorrhage on hepatic injury and interleukin 6 levels.
    Archives of surgery (Chicago, Ill. : 1960), 2004, Volume: 139, Issue:8

    Topics: Analysis of Variance; Animals; Dinoprostone; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; F

2004