pd 98059 has been researched along with Helicobacter Infections in 3 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Helicobacter Infections: Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " pylori lipopolysaccharide (LPS)-induced gastritis was used to study the role of extracellular signal-regulated kinase (ERK) and p38 mitogen-activated protein kinase (MAPK) in the mucosal release of tumor necrosis factor-alpha (TNF-alpha) and endothelin-1 (ET-1) in response to H." | 3.71 | Role of ERK and p38 mitogen-activated protein kinase cascades in gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide. ( Slomiany, A; Slomiany, BL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asim, M | 1 |
| Chaturvedi, R | 1 |
| Hoge, S | 1 |
| Lewis, ND | 1 |
| Singh, K | 1 |
| Barry, DP | 1 |
| Algood, HS | 1 |
| de Sablet, T | 1 |
| Gobert, AP | 1 |
| Wilson, KT | 1 |
| Chang, YJ | 1 |
| Wu, MS | 1 |
| Lin, JT | 1 |
| Pestell, RG | 1 |
| Blaser, MJ | 1 |
| Chen, CC | 1 |
| Slomiany, BL | 1 |
| Slomiany, A | 1 |
3 other studies available for pd 98059 and Helicobacter Infections
| Article | Year |
|---|---|
Helicobacter pylori induces ERK-dependent formation of a phospho-c-Fos c-Jun activator protein-1 complex that causes apoptosis in macrophages.
Topics: Animals; Anthracenes; Apoptosis; Cell Line; Cell Nucleus; Cell Survival; Extracellular Signal-Regula | 2010 |
Mechanisms for Helicobacter pylori CagA-induced cyclin D1 expression that affect cell cycle.
Topics: Antigens, Bacterial; Bacterial Proteins; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Survi | 2006 |
Role of ERK and p38 mitogen-activated protein kinase cascades in gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide.
Topics: Animals; Endothelin-1; Flavonoids; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter | 2001 |