pd 98059 has been researched along with Goiter in 1 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Goiter: Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate in vivo the antiproliferative effect of an inhibitor of isoprenoids metabolism, lovastatin, in an experimental model of propylthiouracil-induced goiter." | 7.73 | HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathway. ( Bifulco, M; Carella, C; Fiorentino, L; Gazzerro, P; Gerbasio, D; Laezza, C; Matarese, G; Mazziotti, G; Portella, G, 2006) |
| "The aim of this study was to evaluate in vivo the antiproliferative effect of an inhibitor of isoprenoids metabolism, lovastatin, in an experimental model of propylthiouracil-induced goiter." | 3.73 | HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathway. ( Bifulco, M; Carella, C; Fiorentino, L; Gazzerro, P; Gerbasio, D; Laezza, C; Matarese, G; Mazziotti, G; Portella, G, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laezza, C | 1 |
| Mazziotti, G | 1 |
| Fiorentino, L | 1 |
| Gazzerro, P | 1 |
| Portella, G | 1 |
| Gerbasio, D | 1 |
| Carella, C | 1 |
| Matarese, G | 1 |
| Bifulco, M | 1 |
1 other study available for pd 98059 and Goiter
| Article | Year |
|---|---|
HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathway.
Topics: Animals; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Transf | 2006 |