Page last updated: 2024-11-02

pd 98059 and Glaucoma

pd 98059 has been researched along with Glaucoma in 2 studies

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"Glaucoma is a neurodegenerative eye disease characterized by gradually impaired visual field and irreversible blindness due to retinal ganglion cell (RGC) loss."5.51Extracellular Signal-Regulated Kinase 1/2 Pathway Is Insufficiently Involved in the Neuroprotective Effect by Hydrogen Sulfide Supplement in Experimental Glaucoma. ( Guo, L; Huang, P; Huang, S; Lin, Z; Liu, X; Shen, X; Yu, H; Zhong, Y, 2019)
"Glaucoma is a neurodegenerative eye disease characterized by gradually impaired visual field and irreversible blindness due to retinal ganglion cell (RGC) loss."1.51Extracellular Signal-Regulated Kinase 1/2 Pathway Is Insufficiently Involved in the Neuroprotective Effect by Hydrogen Sulfide Supplement in Experimental Glaucoma. ( Guo, L; Huang, P; Huang, S; Lin, Z; Liu, X; Shen, X; Yu, H; Zhong, Y, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Huang, S1
Huang, P1
Yu, H1
Lin, Z1
Liu, X1
Shen, X1
Guo, L1
Zhong, Y1
Zhang, X1
Zhang, R1
Chen, J1
Wu, J1

Other Studies

2 other studies available for pd 98059 and Glaucoma

ArticleYear
Extracellular Signal-Regulated Kinase 1/2 Pathway Is Insufficiently Involved in the Neuroprotective Effect by Hydrogen Sulfide Supplement in Experimental Glaucoma.
    Investigative ophthalmology & visual science, 2019, 10-01, Volume: 60, Issue:13

    Topics: Animals; Autophagy; Blotting, Western; Cell Survival; Flavonoids; Glaucoma; Hydrogen Sulfide; In Sit

2019
Neuroprotective effects of DAAO are mediated via the ERK1/2 signaling pathway in a glaucomatous animal model.
    Experimental eye research, 2020, Volume: 190

    Topics: Animals; Blotting, Western; D-Amino-Acid Oxidase; Disease Models, Animal; Ependymoglial Cells; Flavo

2020