pd 98059 has been researched along with Glaucoma in 2 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glaucoma is a neurodegenerative eye disease characterized by gradually impaired visual field and irreversible blindness due to retinal ganglion cell (RGC) loss." | 5.51 | Extracellular Signal-Regulated Kinase 1/2 Pathway Is Insufficiently Involved in the Neuroprotective Effect by Hydrogen Sulfide Supplement in Experimental Glaucoma. ( Guo, L; Huang, P; Huang, S; Lin, Z; Liu, X; Shen, X; Yu, H; Zhong, Y, 2019) |
| "Glaucoma is a neurodegenerative eye disease characterized by gradually impaired visual field and irreversible blindness due to retinal ganglion cell (RGC) loss." | 1.51 | Extracellular Signal-Regulated Kinase 1/2 Pathway Is Insufficiently Involved in the Neuroprotective Effect by Hydrogen Sulfide Supplement in Experimental Glaucoma. ( Guo, L; Huang, P; Huang, S; Lin, Z; Liu, X; Shen, X; Yu, H; Zhong, Y, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, S | 1 |
| Huang, P | 1 |
| Yu, H | 1 |
| Lin, Z | 1 |
| Liu, X | 1 |
| Shen, X | 1 |
| Guo, L | 1 |
| Zhong, Y | 1 |
| Zhang, X | 1 |
| Zhang, R | 1 |
| Chen, J | 1 |
| Wu, J | 1 |
2 other studies available for pd 98059 and Glaucoma
| Article | Year |
|---|---|
Extracellular Signal-Regulated Kinase 1/2 Pathway Is Insufficiently Involved in the Neuroprotective Effect by Hydrogen Sulfide Supplement in Experimental Glaucoma.
Topics: Animals; Autophagy; Blotting, Western; Cell Survival; Flavonoids; Glaucoma; Hydrogen Sulfide; In Sit | 2019 |
Neuroprotective effects of DAAO are mediated via the ERK1/2 signaling pathway in a glaucomatous animal model.
Topics: Animals; Blotting, Western; D-Amino-Acid Oxidase; Disease Models, Animal; Ependymoglial Cells; Flavo | 2020 |