Page last updated: 2024-11-02

pd 98059 and Gastroduodenal Ulcer

pd 98059 has been researched along with Gastroduodenal Ulcer in 1 studies

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.

Research Excerpts

ExcerptRelevanceReference
"However, NSAIDs produce gastroduodenal ulcers in about 25% of users (often with bleeding and/or perforations) and delay ulcer healing, presumably by blocking prostaglandin synthesis from cyclooxygenase (COX)-1 and COX-2 (ref."1.30Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing. ( Itani, RM; Jones, MK; Levin, E; Peskar, BM; Sarfeh, IJ; Tarnawski, AS; Wang, H, 1999)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jones, MK1
Wang, H1
Peskar, BM1
Levin, E1
Itani, RM1
Sarfeh, IJ1
Tarnawski, AS1

Other Studies

1 other study available for pd 98059 and Gastroduodenal Ulcer

ArticleYear
Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing.
    Nature medicine, 1999, Volume: 5, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase

1999