pd 98059 has been researched along with Fibrosarcoma in 6 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study describes the ability of an anthraquinone derivative aloe emodin (AE) to reduce the cytotoxic activity of the platinum(II)-based anticancer agent cisplatin toward murine L929 fibrosarcoma and C6 glioma cell lines." | 3.73 | Aloe emodin decreases the ERK-dependent anticancer activity of cisplatin. ( Kaludjerovic, GN; Maksimovic-Ivanic, D; Mijatovic, S; Miljkovic, D; Radovic, J; Sabo, TJ; Trajkovic, V, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harisi, R | 1 |
| Kenessey, I | 1 |
| Olah, JN | 1 |
| Timar, F | 1 |
| Babo, I | 1 |
| Pogany, G | 1 |
| Paku, S | 1 |
| Jeney, A | 1 |
| Rabelo, FL | 1 |
| Ropert, C | 1 |
| Ramos, MG | 1 |
| Bonjardim, CA | 1 |
| Gazzinelli, RT | 1 |
| Alvarez-Leite, JI | 1 |
| Mijatovic, S | 1 |
| Maksimovic-Ivanic, D | 1 |
| Radovic, J | 1 |
| Miljkovic, D | 1 |
| Kaludjerovic, GN | 1 |
| Sabo, TJ | 1 |
| Trajkovic, V | 1 |
| Kwak, HJ | 1 |
| Park, MJ | 1 |
| Cho, H | 1 |
| Park, CM | 1 |
| Moon, SI | 1 |
| Lee, HC | 1 |
| Park, IC | 1 |
| Kim, MS | 1 |
| Rhee, CH | 1 |
| Hong, SI | 1 |
| Chakrabarti, J | 1 |
| Mitra, A | 1 |
| Banerji, A | 1 |
| Chatterjee, A | 1 |
| Webb, DJ | 1 |
| Nguyen, DH | 1 |
| Gonias, SL | 1 |
6 other studies available for pd 98059 and Fibrosarcoma
| Article | Year |
|---|---|
Differential inhibition of single and cluster type tumor cell migration.
Topics: Adolescent; Bone Neoplasms; Cell Culture Techniques; Cell Movement; Cell Proliferation; Chromones; D | 2009 |
Inhibition of ERK1/2 and CREB phosphorylation by caspase-dependent mechanism enhances apoptosis in a fibrosarcoma cell line treated with butyrate.
Topics: Antineoplastic Agents; Apoptosis; Butyrates; Caspases; Cyclic AMP Response Element-Binding Protein; | 2003 |
Aloe emodin decreases the ERK-dependent anticancer activity of cisplatin.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cisplati | 2005 |
Transforming growth factor-beta1 induces tissue inhibitor of metalloproteinase-1 expression via activation of extracellular signal-regulated kinase and Sp1 in human fibrosarcoma cells.
Topics: Cell Movement; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibrosarcoma; Flavonoi | 2006 |
Culture of human fibrosarcoma HT-1080 cells in presence of fibronectin activates MMP-2.
Topics: Actin Cytoskeleton; Actins; Cell Adhesion; Cell Line, Tumor; Chromones; Culture Media; Enzyme Activa | 2006 |
Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion.
Topics: Aprotinin; Autocrine Communication; Cell Movement; Collagen; Culture Media, Conditioned; Drug Combin | 2000 |