pd 98059 has been researched along with Facial Pain in 2 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Facial Pain: Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the air-puff thresholds (mechanical allodynia), scores of pinprick (mechanical hyperalgesia), and face grooming frequency for acetone application (hypersensitivity for cold stimulation) - 3, 3, 6, 9, 12, 15, 20, 25, 30, and 40 days after surgery." | 1.34 | Intracisternal administration of mitogen-activated protein kinase inhibitors reduced mechanical allodynia following chronic constriction injury of infraorbital nerve in rats. ( Ahn, DK; Han, SR; Jeon, HJ; Ju, JS; Lee, MK; Lim, EJ; Yang, GY, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kobayashi, A | 1 |
| Shinoda, M | 1 |
| Sessle, BJ | 1 |
| Honda, K | 1 |
| Imamura, Y | 1 |
| Hitomi, S | 1 |
| Tsuboi, Y | 1 |
| Okada-Ogawa, A | 1 |
| Iwata, K | 1 |
| Lim, EJ | 1 |
| Jeon, HJ | 1 |
| Yang, GY | 1 |
| Lee, MK | 1 |
| Ju, JS | 1 |
| Han, SR | 1 |
| Ahn, DK | 1 |
2 other studies available for pd 98059 and Facial Pain
| Article | Year |
|---|---|
Mechanisms involved in extraterritorial facial pain following cervical spinal nerve injury in rats.
Topics: Animals; Astrocytes; Behavior, Animal; Cervical Vertebrae; Extracellular Signal-Regulated MAP Kinase | 2011 |
Intracisternal administration of mitogen-activated protein kinase inhibitors reduced mechanical allodynia following chronic constriction injury of infraorbital nerve in rats.
Topics: Animals; Behavior, Animal; Body Weight; Constriction; Disease Models, Animal; Dose-Response Relation | 2007 |