pd 98059 has been researched along with Di Guglielmo Disease in 9 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Another human erythroleukemia cell line (K562) and the human monocyte tumor cell line U937 showed 5." | 1.31 | Differential inhibition by alpha- and beta-tocopherol of human erythroleukemia cell adhesion: role of integrins. ( Azzi, A; Breyer, I, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 7 (77.78) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akiyama, M | 1 |
| Kawano, T | 1 |
| Mikami-Terao, Y | 1 |
| Agawa-Ohta, M | 1 |
| Yamada, O | 1 |
| Ida, H | 1 |
| Yamada, H | 1 |
| Schaefer, A | 1 |
| Kósa, F | 1 |
| Bittorf, T | 1 |
| Magócsi, M | 1 |
| Rosche, A | 1 |
| Ramirez-Chávez, Y | 1 |
| Marotzki, S | 1 |
| Marquardt, H | 1 |
| Lunghi, P | 1 |
| Costanzo, A | 1 |
| Levrero, M | 1 |
| Bonati, A | 1 |
| Herrera, R | 1 |
| Hubbell, S | 1 |
| Decker, S | 1 |
| Petruzzelli, L | 1 |
| Hayakawa, F | 1 |
| Towatari, M | 1 |
| Kiyoi, H | 1 |
| Tanimoto, M | 1 |
| Kitamura, T | 1 |
| Saito, H | 1 |
| Naoe, T | 1 |
| Matsuzaki, T | 1 |
| Aisaki, Ki | 1 |
| Yamamura, Y | 1 |
| Noda, M | 1 |
| Ikawa, Y | 1 |
| Honma, Y | 1 |
| Ishii, Y | 1 |
| Kasukabe, T | 1 |
| Okabe-Kado, J | 1 |
| Yamamoto-Yamaguchi, Y | 1 |
| Kakegawa, T | 1 |
| Awaya, A | 1 |
| Kalina, U | 1 |
| Koschmieder, S | 1 |
| Hofmann, WK | 1 |
| Wagner, S | 1 |
| Kauschat, D | 1 |
| Hoelzer, D | 1 |
| Ottmann, OG | 1 |
| Breyer, I | 1 |
| Azzi, A | 1 |
9 other studies available for pd 98059 and Di Guglielmo Disease
| Article | Year |
|---|---|
Erythropoietin activates telomerase through transcriptional and posttranscriptional regulation in human erythroleukemic JAS-REN-A cells.
Topics: Blotting, Western; Erythropoietin; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expr | 2011 |
Opposite effects of inhibitors of mitogen-activated protein kinase pathways on the egr-1 and beta-globin expression in erythropoietin-responsive murine erythroleukemia cells.
Topics: Animals; Butadienes; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Inhibitors; Eryth | 2004 |
Treatment with arsenic trioxide (ATO) and MEK1 inhibitor activates the p73-p53AIP1 apoptotic pathway in leukemia cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Arsenic Trioxide; Arsenicals; Benza | 2004 |
A role for the MEK/MAPK pathway in PMA-induced cell cycle arrest: modulation of megakaryocytic differentiation of K562 cells.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion; Cell Adhesion Molecules; Cell Cycle; Ce | 1998 |
Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines.
Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cell Division; DNA-Bi | 2000 |
Induction of erythroid differentiation by inhibition of Ras/ERK pathway in a friend murine leukemia cell line.
Topics: Androstadienes; Animals; Cell Differentiation; Dimethyl Sulfoxide; Down-Regulation; Enzyme Inhibitor | 2000 |
Induction of differentiation of human myeloid leukemia cells by novel synthetic neurotrophic pyrimidine derivatives.
Topics: Calcitriol; Cell Differentiation; Cell Division; Enzyme Activation; Enzyme Inhibitors; Flavonoids; G | 2001 |
Transforming growth factor-beta1 interferes with thrombopoietin-induced signal transduction in megakaryoblastic and erythroleukemic cells.
Topics: Cell Differentiation; Cell Division; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Ery | 2001 |
Differential inhibition by alpha- and beta-tocopherol of human erythroleukemia cell adhesion: role of integrins.
Topics: Antibodies, Monoclonal; Cell Adhesion; Down-Regulation; Flavonoids; Flow Cytometry; Humans; Integrin | 2001 |