pd 98059 has been researched along with Dementias, Transmissible in 1 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prion diseases are neurodegenerative pathologies characterized by the accumulation in the brain of a protease-resistant form of the prion protein (PrP(c)), named PrP(Sc)." | 1.31 | p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells. ( Arena, S; Benatti, U; Corsaro, A; Damonte, G; Florio, T; Millo, E; Schettini, G; Tagliavini, F; Thellung, S; Villa, V, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thellung, S | 1 |
| Villa, V | 1 |
| Corsaro, A | 1 |
| Arena, S | 1 |
| Millo, E | 1 |
| Damonte, G | 1 |
| Benatti, U | 1 |
| Tagliavini, F | 1 |
| Florio, T | 1 |
| Schettini, G | 1 |
1 other study available for pd 98059 and Dementias, Transmissible
| Article | Year |
|---|---|
p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Enz | 2002 |