pd 98059 has been researched along with Degenerative Disc Disease in 4 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intervertebral disc degeneration (IDD) has become the most common cause of low‑back pain, and it imposes a heavy burden on patients with IDD and society." | 1.48 | Long non‑coding RNA FAF1 promotes intervertebral disc degeneration by targeting the Erk signaling pathway. ( Cai, C; Huang, W; Liu, X; Lu, W; Ma, P; Mi, D; Shen, S; Zhou, B, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mi, D | 1 |
| Cai, C | 1 |
| Zhou, B | 1 |
| Liu, X | 1 |
| Ma, P | 1 |
| Shen, S | 1 |
| Lu, W | 1 |
| Huang, W | 1 |
| Wang, T | 1 |
| Wang, CJ | 1 |
| Tian, S | 1 |
| Song, HB | 1 |
| Xiong, C | 1 |
| Huang, Y | 1 |
| Kang, H | 1 |
| Zhang, T | 1 |
| Xu, F | 1 |
| Cai, X | 1 |
| Hiyama, A | 1 |
| Sakai, D | 1 |
| Tanaka, M | 1 |
| Arai, F | 1 |
| Nakajima, D | 1 |
| Abe, K | 1 |
| Mochida, J | 1 |
4 other studies available for pd 98059 and Degenerative Disc Disease
| Article | Year |
|---|---|
Long non‑coding RNA FAF1 promotes intervertebral disc degeneration by targeting the Erk signaling pathway.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Apoptosis Regulatory Proteins; Cell Proliferation | 2018 |
Overexpressed IGFBP5 promotes cell proliferation and inhibits apoptosis of nucleus pulposus derived from rats with disc degeneration through inactivating the ERK/MAPK axis.
Topics: Animals; Apoptosis; Cell Proliferation; Flavonoids; Gene Expression Regulation; Insulin-Like Growth | 2019 |
Macrophage Inhibition Factor-Mediated CD74 Signal Modulate Inflammation and Matrix Metabolism in the Degenerated Cartilage Endplate Chondrocytes by Activating Extracellular Signal Regulated Kinase 1/2.
Topics: Adult; Antigens, Differentiation, B-Lymphocyte; Chondrocytes; Female; Flavonoids; Gene Expression; H | 2017 |
The relationship between the Wnt/β-catenin and TGF-β/BMP signals in the intervertebral disc cell.
Topics: Animals; beta Catenin; Bone Morphogenetic Protein 2; Cell Line; Cell Proliferation; Cyclin D1; Extra | 2011 |