Page last updated: 2024-11-02

pd 98059 and Craniofacial Pain

pd 98059 has been researched along with Craniofacial Pain in 2 studies

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.

Research Excerpts

ExcerptRelevanceReference
"We examined the air-puff thresholds (mechanical allodynia), scores of pinprick (mechanical hyperalgesia), and face grooming frequency for acetone application (hypersensitivity for cold stimulation) - 3, 3, 6, 9, 12, 15, 20, 25, 30, and 40 days after surgery."1.34Intracisternal administration of mitogen-activated protein kinase inhibitors reduced mechanical allodynia following chronic constriction injury of infraorbital nerve in rats. ( Ahn, DK; Han, SR; Jeon, HJ; Ju, JS; Lee, MK; Lim, EJ; Yang, GY, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kobayashi, A1
Shinoda, M1
Sessle, BJ1
Honda, K1
Imamura, Y1
Hitomi, S1
Tsuboi, Y1
Okada-Ogawa, A1
Iwata, K1
Lim, EJ1
Jeon, HJ1
Yang, GY1
Lee, MK1
Ju, JS1
Han, SR1
Ahn, DK1

Other Studies

2 other studies available for pd 98059 and Craniofacial Pain

ArticleYear
Mechanisms involved in extraterritorial facial pain following cervical spinal nerve injury in rats.
    Molecular pain, 2011, Feb-10, Volume: 7

    Topics: Animals; Astrocytes; Behavior, Animal; Cervical Vertebrae; Extracellular Signal-Regulated MAP Kinase

2011
Intracisternal administration of mitogen-activated protein kinase inhibitors reduced mechanical allodynia following chronic constriction injury of infraorbital nerve in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Aug-15, Volume: 31, Issue:6

    Topics: Animals; Behavior, Animal; Body Weight; Constriction; Disease Models, Animal; Dose-Response Relation

2007