pd 98059 has been researched along with Constriction, Pathologic in 3 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Constriction, Pathologic: The condition of an anatomical structure's being constricted beyond normal dimensions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to investigate the role of angiotensin II (Ang II), a major inducer of cardiac hypertrophy, in the reexpression of T-type channel in left ventricular hypertrophied myocytes." | 3.72 | Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels. ( Capuano, V; Coulombe, A; Deroubaix, E; Ferron, L; Renaud, JF; Ruchon, Y, 2003) |
| "In an in vitro model of PE-induced cardiac hypertrophy, Selumetinib significantly inhibited the ERK activation and prevented enlargement of cardiomyocytes or reactivation of certain fetal genes." | 1.43 | Selumetinib, an Oral Anti-Neoplastic Drug, May Attenuate Cardiac Hypertrophy via Targeting the ERK Pathway. ( Cai, H; Chen, L; Chen, Z; Li, C; Li, S; Li, Y; Long, D; Luo, F; Rao, L; Yang, H; You, G; Zhang, Q, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, C | 1 |
| Chen, Z | 1 |
| Yang, H | 1 |
| Luo, F | 1 |
| Chen, L | 1 |
| Cai, H | 1 |
| Li, Y | 1 |
| You, G | 1 |
| Long, D | 1 |
| Li, S | 1 |
| Zhang, Q | 1 |
| Rao, L | 1 |
| Ferron, L | 1 |
| Capuano, V | 1 |
| Ruchon, Y | 1 |
| Deroubaix, E | 1 |
| Coulombe, A | 1 |
| Renaud, JF | 1 |
| Andrassy, M | 1 |
| Belov, D | 1 |
| Harja, E | 1 |
| Zou, YS | 1 |
| Leitges, M | 1 |
| Katus, HA | 1 |
| Nawroth, PP | 1 |
| Yan, SD | 1 |
| Schmidt, AM | 1 |
| Yan, SF | 1 |
3 other studies available for pd 98059 and Constriction, Pathologic
| Article | Year |
|---|---|
Selumetinib, an Oral Anti-Neoplastic Drug, May Attenuate Cardiac Hypertrophy via Targeting the ERK Pathway.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Aorta; Apoptosis; Benzimidazoles; Cardiomegaly | 2016 |
Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Bosentan; Butadienes; C | 2003 |
Central role of PKCbeta in neointimal expansion triggered by acute arterial injury.
Topics: Animals; Aorta; Blood Glucose; Cell Division; Cell Movement; Cells, Cultured; Constriction, Patholog | 2005 |