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pd 98059 and Colonic Neoplasms

pd 98059 has been researched along with Colonic Neoplasms in 49 studies

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"When colon cancer cells became crowded, the increase in αvβ6 levels at the cell surface was not accompanied by a change in total αvβ6 expression in cell lysates."1.37PKC promotes the migration of colon cancer cells by regulating the internalization and recycling of integrin αvβ6. ( Agrez, M; Chen, R; Hong, J; Liu, E; Liu, S; Niu, J; Niu, W; Peng, C; Wang, J; Wu, J; Xu, K, 2011)
"The treatment of the colon cancer cell lines SW480 and DLD-1 with paclitaxel resulted in increased activation of the MAPK pathway, which was blocked by PD98059, a MEK inhibitor."1.35Enhancement of paclitaxel-induced apoptosis by inhibition of mitogen-activated protein kinase pathway in colon cancer cells. ( Akiyoshi, T; Katano, M; Koga, K; Mibu, R; Nagai, S; Nakamura, M; Sato, N; Wada, J; Xu, R; Yanai, K, 2009)
"In the human colon cancer cell line SW1116, treatment with the DNA methyltransferase 1 (DNMT1) inhibitor 5-aza-2'-deoxycytidine (5-aza-dC) or the ERK-MAPK inhibitors PD98059 or rottlerin, or transient transfection with the MAP/ERK kinase (MEK)1/2 small interfering RNA down-regulates DNMT1 and proliferating cell nuclear antigen levels."1.34Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells. ( Chen, ZF; Fang, JY; Lu, R; Sun, DF; Tian, XQ; Wang, X, 2007)
"Sulindac sulfide treatment was associated with activation of ERKp44/42 and p38 MAPK in a dosage- and time-dependent manner, and also activated upstream MEK."1.33Selective inhibitors of MEK1/ERK44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells. ( Sinicrope, FA; Sun, Y, 2005)
"Sulindac sulfone (exisulind), is a promising anticancer agent because of its ability to induce apoptosis in a variety of malignant cell types and its minimal toxicity to normal cells."1.33p38MAPK inhibitor SB203580 sensitizes human SNU-C4 colon cancer cells to exisulind-induced apoptosis. ( Lee, E; Lee, YJ; Lim, SJ, 2006)
"Some human colon cancer cell lines (e."1.32Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells. ( Cheng, K; Raufman, JP; Zimniak, P, 2003)
"Human colon cancer cells (Caco-2) were stimulated with increasing concentrations of sodium chloride (NaCl) or LPS."1.31Epithelial cyclooxygenase-2 expression: a model for pathogenesis of colon cancer. ( Arbabi, S; Garcia, I; Jelacic, S; Maier, RV; Rosengart, MR, 2001)
"Since human colon cancers often contain significant quantities of progastrin-processing intermediates, we sought to explore the possibility that the biosynthetic precursor of fully processed amidated gastrin, glycine-extended gastrin, may exert trophic effects on human colonic cancer cells."1.30Glycine-extended gastrin exerts growth-promoting effects on human colon cancer cells. ( Dickinson, CJ; Sawada, M; Stepan, VM; Todisco, A, 1999)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (8.16)18.2507
2000's37 (75.51)29.6817
2010's8 (16.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akao, Y1
Kumazaki, M1
Shinohara, H1
Sugito, N1
Kuranaga, Y1
Tsujino, T1
Yoshikawa, Y1
Kitade, Y1
Kline, CL1
Olson, TL1
Irby, RB1
Park, YS1
Cho, NJ1
Xu, R1
Sato, N1
Yanai, K1
Akiyoshi, T1
Nagai, S1
Wada, J1
Koga, K1
Mibu, R1
Nakamura, M1
Katano, M1
Lee, SJ1
Park, K1
Ha, SD1
Kim, WJ1
Moon, SK1
Yaguchi, T1
Saito, M1
Yasuda, Y1
Kanno, T1
Nakano, T1
Nishizaki, T1
Ebert, B2
Kisiela, M1
Malátková, P1
El-Hawari, Y1
Maser, E1
Lu, J1
Liu, K1
Zhao, J2
Ma, J1
Yang, H1
Huang, Y1
Qin, Z1
Bai, R1
Jiang, L1
Lv, F1
Li, P1
Yan, W1
Zhao, M1
Dong, Z1
Luo, DX1
Peng, XH1
Xiong, Y1
Liao, DF1
Cao, D1
Li, L1
Wang, J3
Wu, J2
Hong, J1
Chen, R1
Xu, K1
Niu, W1
Peng, C1
Liu, E1
Liu, S1
Agrez, M1
Niu, J1
Duerr, EM1
Mizukami, Y1
Moriichi, K1
Gala, M1
Jo, WS1
Kikuchi, H1
Xavier, RJ1
Chung, DC2
Thamilselvan, V1
Li, W1
Sumpio, BE1
Basson, MD1
Lin, SY1
Liang, YC1
Ho, YS1
Tsai, SH1
Pan, S1
Lee, WS1
Sawhney, RS1
Sharma, B1
Humphrey, LE1
Brattain, MG2
Darmoul, D1
Gratio, V1
Devaud, H1
Lehy, T1
Laburthe, M1
Hori, H1
Nakata, H2
Iguchi, G1
Yamada, H1
Chihara, K1
Baba, H1
Jikuhara, A2
Yoshii, M2
Iwagaki, H2
Mori, S2
Nishibori, M2
Tanaka, N2
Cheng, K1
Zimniak, P1
Raufman, JP1
Wang, X4
Wang, Q1
Hu, W1
Evers, BM1
Satsu, H1
Manabe, M1
Shimizu, M1
Tominaga, K1
Higuchi, K1
Sasaki, E1
Suto, R1
Watanabe, T1
Fujiwara, Y1
Oshitani, N1
Matsumoto, T1
Kim, S1
Iwao, H1
Arakawa, T1
Sun, Y1
Sinicrope, FA1
Drosopoulos, KG1
Roberts, ML1
Cermak, L1
Sasazuki, T1
Shirasawa, S1
Andera, L1
Pintzas, A1
Demidenko, ZN1
Halicka, D1
Kunicki, J1
McCubrey, JA1
Darzynkiewicz, Z1
Blagosklonny, MV1
Seidel, A1
Lampen, A1
Oehme, I1
Bösser, S1
Zörnig, M1
Takahashi, HK1
Kim, IA1
Bae, SS1
Fernandes, A1
Muschel, RJ1
McKenna, WG1
Birnbaum, MJ1
Bernhard, EJ1
Jeon, HK1
Choi, SU1
Jung, NP1
Woo, KJ1
Lee, TJ1
Park, JW1
Kwon, TK1
Li, M1
Yeung, CM1
Zhang, H1
Kung, HF1
Jiang, B1
Lin, MC1
Díaz, VM1
Hurtado, M1
Kort, EJ1
Resnati, M1
Blasi, F1
Thomson, T1
Paciucci, R1
Lim, SJ1
Lee, YJ1
Lee, E1
Lu, R1
Chen, ZF1
Sun, DF1
Tian, XQ1
Fang, JY1
Deng, H1
Ravikumar, TS1
Yang, WL1
Saha, S1
Chowdhury, P1
Pal, A1
Chakrabarti, MK1
Tang, JQ1
Wan, YL1
Liu, YC1
Rong, L1
Wu, T1
Pan, YS1
Zhu, J1
Liang, FP1
Lin, CH1
Kuo, CD1
Chao, HP1
Fu, SL1
Lengyel, E1
Wang, H1
Gum, R1
Simon, C1
Wang, Y1
Boyd, D1
Wang, SL1
Westwick, JK1
Tillotson, LG1
Stepan, VM1
Sawada, M1
Todisco, A1
Dickinson, CJ1
Jung, YD1
Nakano, K1
Liu, W1
Gallick, GE1
Ellis, LM1
Kinugasa, T1
Sakaguchi, T1
Gu, X1
Reinecker, HC1
Kinoshita, K1
Taupin, DR1
Itoh, H1
Podolsky, DK1
Ogier-Denis, E1
Pattingre, S1
El Benna, J1
Codogno, P1
Qiao, D1
Stratagouleas, ED1
Martinez, JD1
Ruhland, A1
de Villiers, EM1
Arbabi, S1
Rosengart, MR1
Garcia, I1
Jelacic, S1
Maier, RV1
Venkateswarlu, S1
Dawson, DM1
St Clair, P1
Gupta, A1
Willson, JK1

Other Studies

49 other studies available for pd 98059 and Colonic Neoplasms

ArticleYear
Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143.
    Cancer science, 2018, Volume: 109, Issue:5

    Topics: Animals; Benzimidazoles; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloni

2018
Src activity alters alpha3 integrin expression in colon tumor cells.
    Clinical & experimental metastasis, 2009, Volume: 26, Issue:2

    Topics: Cell Adhesion; Cell Line, Tumor; Cell Movement; Chromones; Colonic Neoplasms; Down-Regulation; Extra

2009
Enhanced proliferation of SNU-407 human colon cancer cells by muscarinic acetylcholine receptors.
    BMB reports, 2008, Nov-30, Volume: 41, Issue:11

    Topics: Atropine; Carbachol; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Flavonoids;

2008
Enhancement of paclitaxel-induced apoptosis by inhibition of mitogen-activated protein kinase pathway in colon cancer cells.
    Anticancer research, 2009, Volume: 29, Issue:1

    Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Flavonoids; Human

2009
Gleditsia sinensis thorn extract inhibits human colon cancer cells: the role of ERK1/2, G2/M-phase cell cycle arrest and p53 expression.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:12

    Topics: Animals; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; D

2010
Higher concentrations of extracellular ATP suppress proliferation of Caco-2 human colonic cancer cells via an unknown receptor involving PKC inhibition.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2010, Volume: 26, Issue:2

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Caco-2 Cells; Cell Proliferation; Cell Survival; Colo

2010
Regulation of human carbonyl reductase 3 (CBR3; SDR21C2) expression by Nrf2 in cultured cancer cells.
    Biochemistry, 2010, Oct-05, Volume: 49, Issue:39

    Topics: Alcohol Oxidoreductases; Animals; Cell Line; Cell Line, Tumor; Colonic Neoplasms; Cricetinae; Enzyme

2010
VEGF-A not Ang2 mediates endothelial-like differentiation of immature DCs by ERK1/2 signaling in the microenvironment of human colon adenocarcinoma.
    International journal of oncology, 2011, Volume: 38, Issue:6

    Topics: Adenocarcinoma; Angiopoietin-2; Cell Differentiation; Cells, Cultured; Colonic Neoplasms; Culture Me

2011
Dual role of insulin-like growth factor-1 in acetyl-CoA carboxylase-alpha activity in human colon cancer cells HCT-8: downregulating its expression and phosphorylation.
    Molecular and cellular biochemistry, 2011, Volume: 357, Issue:1-2

    Topics: Acetyl-CoA Carboxylase; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumo

2011
PKC promotes the migration of colon cancer cells by regulating the internalization and recycling of integrin αvβ6.
    Cancer letters, 2011, Dec-01, Volume: 311, Issue:1

    Topics: Amino Acid Sequence; Antigens, Neoplasm; Binding Sites; Cell Membrane; Cell Movement; Colonic Neopla

2011
Oncogenic KRAS regulates BMP4 expression in colon cancer cell lines.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, May-15, Volume: 302, Issue:10

    Topics: Bone Morphogenetic Protein 4; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Cell P

2012
Sphingosine-1-phosphate stimulates human Caco-2 intestinal epithelial proliferation via p38 activation and activates ERK by an independent mechanism.
    In vitro cellular & developmental biology. Animal, 2002, Volume: 38, Issue:4

    Topics: Caco-2 Cells; Cell Division; Colonic Neoplasms; Dimethyl Sulfoxide; Dose-Response Relationship, Drug

2002
Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells.
    Molecular carcinogenesis, 2002, Volume: 35, Issue:1

    Topics: Adenocarcinoma; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Chromosome Mapping; Colonic Neoplasms

2002
Integrin alpha2 and extracellular signal-regulated kinase are functionally linked in highly malignant autocrine transforming growth factor-alpha-driven colon cancer cells.
    The Journal of biological chemistry, 2003, May-30, Volume: 278, Issue:22

    Topics: Butadienes; Chromones; Colonic Neoplasms; Enzyme Inhibitors; Flavonoids; Humans; Integrin alpha2; Mi

2003
Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells.
    The American journal of pathology, 2003, Volume: 162, Issue:5

    Topics: Calcium; Cell Division; Cell Movement; Colonic Neoplasms; Enzyme Inhibitors; Flavonoids; Gene Expres

2003
Oncogenic ras induces gastrin/CCKB receptor gene expression in human colon cancer cell lines LoVo and Colo320HSR.
    The Journal of laboratory and clinical medicine, 2003, Volume: 141, Issue:5

    Topics: Base Sequence; Colonic Neoplasms; DNA Primers; Enzyme Inhibitors; Flavonoids; Gene Expression Regula

2003
MAP kinase-mediated proliferation of DLD-1 carcinoma by the stimulation of protease-activated receptor 2.
    Life sciences, 2003, Oct-17, Volume: 73, Issue:22

    Topics: Calcium; Carcinoma; Cell Division; Colonic Neoplasms; Cytosol; Flavonoids; Humans; Immunoblotting; I

2003
Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells.
    Cancer research, 2003, Oct-15, Volume: 63, Issue:20

    Topics: Acetylcholine; Animals; Atropine; Cell Division; CHO Cells; Cholinergic Agonists; Colonic Neoplasms;

2003
Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-kappaB-dependent pathway.
    Oncogene, 2004, Mar-11, Volume: 23, Issue:10

    Topics: Cell Line, Tumor; Colonic Neoplasms; Dactinomycin; Enzyme Inhibitors; Flavonoids; Gene Expression Re

2004
Activation of Ca2+/calmodulin-dependent protein kinase II is involved in hyperosmotic induction of the human taurine transporter.
    FEBS letters, 2004, Jul-02, Volume: 569, Issue:1-3

    Topics: Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Prote

2004
Correlation of MAP kinases with COX-2 induction differs between MKN45 and HT29 cells.
    Alimentary pharmacology & therapeutics, 2004, Volume: 20 Suppl 1

    Topics: Blotting, Western; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygen

2004
Selective inhibitors of MEK1/ERK44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase Inhibitors; Dr

2005
Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway.
    The Journal of biological chemistry, 2005, Jun-17, Volume: 280, Issue:24

    Topics: Androstadienes; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Separation; Cell Su

2005
Selective killing of adriamycin-resistant (G2 checkpoint-deficient and MRP1-expressing) cancer cells by docetaxel.
    Cancer research, 2005, May-15, Volume: 65, Issue:10

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms

2005
Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists.
    Carcinogenesis, 2005, Volume: 26, Issue:10

    Topics: Adenocarcinoma; Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; AT

2005
Agonists of an ecdysone-inducible mammalian expression system inhibit Fas Ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO.
    Cell death and differentiation, 2006, Volume: 13, Issue:2

    Topics: Androstadienes; Apoptosis; Apoptosis Regulatory Proteins; bcl-X Protein; Caspase 8; Caspases; Cell C

2006
Mast cell tryptase stimulates DLD-1 carcinoma through prostaglandin- and MAP kinase-dependent manners.
    Journal of pharmacological sciences, 2005, Volume: 98, Issue:4

    Topics: Benzamidines; Calcium; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclooxyg

2005
Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines.
    Cancer research, 2005, Sep-01, Volume: 65, Issue:17

    Topics: Animals; Carcinoma; Cell Survival; Chromones; Colonic Neoplasms; Enzyme Inhibitors; Flavonoids; Huma

2005
Association of the ERK1/2 and p38 kinase pathways with nitric oxide-induced apoptosis and cell cycle arrest in colon cancer cells.
    Cell biology and toxicology, 2005, Volume: 21, Issue:2

    Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Colonic Neoplasms; Enzyme Activation; Flavonoids; Glutathio

2005
Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway.
    Biochemical and biophysical research communications, 2006, Apr-28, Volume: 343, Issue:1

    Topics: Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Deferoxamine; Ferric Compounds; Fl

2006
The BH3-only protein, PUMA, is involved in oxaliplatin-induced apoptosis in colon cancer cells.
    Biochemical pharmacology, 2006, May-28, Volume: 71, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Colonic Neoplasms

2006
Requirement of the enzymatic and signaling activities of plasmin for phorbol-ester-induced scattering of colon cancer cells.
    Experimental cell research, 2006, Jul-15, Volume: 312, Issue:12

    Topics: Aminocaproic Acid; Cell Movement; Colonic Neoplasms; Culture Media, Serum-Free; Enzyme Inhibitors; E

2006
p38MAPK inhibitor SB203580 sensitizes human SNU-C4 colon cancer cells to exisulind-induced apoptosis.
    Oncology reports, 2006, Volume: 16, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Colonic Neoplasms; Flavonoids; HCT116 Cel

2006
Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells.
    The Journal of biological chemistry, 2007, Apr-20, Volume: 282, Issue:16

    Topics: Acetophenones; Base Sequence; Benzopyrans; Cell Line, Tumor; Colonic Neoplasms; Cyclin-Dependent Kin

2007
Bone morphogenetic protein-4 inhibits heat-induced apoptosis by modulating MAPK pathways in human colon cancer HCT116 cells.
    Cancer letters, 2007, Oct-28, Volume: 256, Issue:2

    Topics: Adenocarcinoma; Apoptosis; bcl-2-Associated X Protein; Bone Morphogenetic Protein 4; Bone Morphogene

2007
Downregulation of human colon carcinoma cell (COLO-205) proliferation through PKG-MAP kinase mediated signaling cascade by E. coli heat stable enterotoxin (STa), a potent anti-angiogenic and anti-metastatic molecule.
    Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:4

    Topics: Aminoquinolines; Angiogenesis Inhibitors; Bacterial Toxins; Blotting, Western; Carbazoles; Cell Line

2008
[Regulation of promatrilysin expression by tissue factor/actived coagulation factor VII complex in LoVo colon cancer cell line].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2007, Oct-18, Volume: 39, Issue:5

    Topics: Anthracenes; Cell Line, Tumor; Colonic Neoplasms; Enzyme Inhibitors; Enzyme Precursors; Factor VII;

2007
Suppression of v-Src transformation by andrographolide via degradation of the v-Src protein and attenuation of the Erk signaling pathway.
    The Journal of biological chemistry, 2008, Feb-22, Volume: 283, Issue:8

    Topics: Antiviral Agents; Butadienes; Cell Line, Tumor; Cell Transformation, Neoplastic; Colonic Neoplasms;

2008
Elevated urokinase-type plasminogen activator receptor expression in a colon cancer cell line is due to a constitutively activated extracellular signal-regulated kinase-1-dependent signaling cascade.
    Oncogene, 1997, May-29, Volume: 14, Issue:21

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Colonic Neoplasms; Dual Specifici

1997
Oncogenic ras induces gastrin gene expression in colon cancer.
    Gastroenterology, 1998, Volume: 115, Issue:5

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Colonic Neoplasms; Enzyme Inhibitors; Flavonoids; Gast

1998
Glycine-extended gastrin exerts growth-promoting effects on human colon cancer cells.
    Molecular medicine (Cambridge, Mass.), 1999, Volume: 5, Issue:3

    Topics: Animals; Antineoplastic Agents; Binding Sites; Binding, Competitive; Calcium-Calmodulin-Dependent Pr

1999
Extracellular signal-regulated kinase activation is required for up-regulation of vascular endothelial growth factor by serum starvation in human colon carcinoma cells.
    Cancer research, 1999, Oct-01, Volume: 59, Issue:19

    Topics: Cell Line; Colonic Neoplasms; Culture Media, Serum-Free; Endothelial Growth Factors; Enzyme Activati

1999
Claudins regulate the intestinal barrier in response to immune mediators.
    Gastroenterology, 2000, Volume: 118, Issue:6

    Topics: Blotting, Northern; Claudin-1; Claudins; Colonic Neoplasms; Electric Impedance; Enzyme Inhibitors; E

2000
Distinct pathways of cell migration and antiapoptotic response to epithelial injury: structure-function analysis of human intestinal trefoil factor.
    Molecular and cellular biology, 2000, Volume: 20, Issue:13

    Topics: Amino Acid Sequence; Animals; Apoptosis; Cell Movement; Colonic Neoplasms; Enzyme Inhibitors; Epithe

2000
Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells.
    The Journal of biological chemistry, 2000, Dec-15, Volume: 275, Issue:50

    Topics: Alanine; Casein Kinase II; Colonic Neoplasms; Enzyme Inhibitors; Flavonoids; GTP Phosphohydrolases;

2000
Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis.
    Carcinogenesis, 2001, Volume: 22, Issue:1

    Topics: Apoptosis; Colonic Neoplasms; Deoxycholic Acid; Down-Regulation; Enzyme Activation; Enzyme Inhibitor

2001
Opposite regulation of the HPV 20-URR and HPV 27-URR promoters by ultraviolet irradiation and cytokines.
    International journal of cancer, 2001, Mar-15, Volume: 91, Issue:6

    Topics: Androstadienes; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Chloramphenicol O-Acetyltransfera

2001
Epithelial cyclooxygenase-2 expression: a model for pathogenesis of colon cancer.
    The Journal of surgical research, 2001, May-01, Volume: 97, Issue:1

    Topics: Carcinoma; Colonic Neoplasms; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Inhibitors;

2001
Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells.
    Oncogene, 2002, Jan-03, Volume: 21, Issue:1

    Topics: Adenocarcinoma; Apoptosis; Autocrine Communication; Cell Cycle; Chromones; Colonic Neoplasms; Cultur

2002