pd 98059 has been researched along with Cardiac Remodeling, Ventricular in 6 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Post-myocardial infarction ventricular remodeling is associated with the expression of a variety of factors including S100B that can potentially modulate myocyte apoptosis." | 1.36 | S100B interaction with the receptor for advanced glycation end products (RAGE): a novel receptor-mediated mechanism for myocyte apoptosis postinfarction. ( Desjardins, JF; Huttunen, HJ; Izhar, S; Leong-Poi, H; Parker, TG; Tsoporis, JN, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, Y | 1 |
| Xie, KL | 1 |
| Wu, HL | 1 |
| Wu, K | 1 |
| Jing, L | 1 |
| Li, WM | 1 |
| Zhou, LJ | 1 |
| Li, S | 1 |
| Kou, JJ | 1 |
| Song, J | 1 |
| Tsoporis, JN | 1 |
| Izhar, S | 1 |
| Leong-Poi, H | 1 |
| Desjardins, JF | 1 |
| Huttunen, HJ | 1 |
| Parker, TG | 1 |
| Kapoun, AM | 1 |
| Liang, F | 1 |
| O'Young, G | 1 |
| Damm, DL | 1 |
| Quon, D | 1 |
| White, RT | 1 |
| Munson, K | 1 |
| Lam, A | 1 |
| Schreiner, GF | 1 |
| Protter, AA | 1 |
| Pantos, C | 1 |
| Xinaris, C | 1 |
| Mourouzis, I | 1 |
| Malliopoulou, V | 1 |
| Kardami, E | 1 |
| Cokkinos, DV | 1 |
| Kumbar, DH | 1 |
| VanBergen, A | 1 |
| Ocampo, C | 1 |
| Muangmingsuk, S | 1 |
| Griffin, AJ | 1 |
| Gupta, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Study Of The Usage Of Statins In A Community Heart Failure Population: The Impact of HMG Co-Enzyme A Reductase Inhibitors on Heart Structural Parameters, Brain Naturetic Peptide, Markers of Inflammation and Fibrosis[NCT00795912] | Phase 4 | 56 participants (Actual) | Interventional | 2003-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for pd 98059 and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Functional suppression of Epiregulin impairs angiogenesis and aggravates left ventricular remodeling by disrupting the extracellular-signal-regulated kinase1/2 signaling pathway in rats after acute myocardial infarction.
Topics: Animals; Diastole; Electrocardiography; Epiregulin; Flavonoids; Heart Function Tests; Hemodynamics; | 2019 |
Expression of renin-angiotensin system and peroxisome proliferator-activated receptors in alcoholic cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Bi | 2008 |
S100B interaction with the receptor for advanced glycation end products (RAGE): a novel receptor-mediated mechanism for myocyte apoptosis postinfarction.
Topics: Animals; Apoptosis; Butadienes; Caspase 3; Cell Line; Cytochromes c; Cytosol; Disease Models, Animal | 2010 |
B-type natriuretic peptide exerts broad functional opposition to transforming growth factor-beta in primary human cardiac fibroblasts: fibrosis, myofibroblast conversion, proliferation, and inflammation.
Topics: Adolescent; Blotting, Western; Butadienes; Cell Division; Cells, Cultured; Cyclic GMP; Enzyme Inhibi | 2004 |
Thyroid hormone changes cardiomyocyte shape and geometry via ERK signaling pathway: potential therapeutic implications in reversing cardiac remodeling?
Topics: Animals; Animals, Newborn; Cell Shape; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Flavono | 2007 |
Adapter molecule DOC-2 is differentially expressed in pressure and volume overload hypertrophy and inhibits collagen synthesis in cardiac fibroblasts.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Angiotensin II; Animals | 2007 |