pd 98059 has been researched along with Cardiac Failure in 5 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Angiotensin II (Ang II), acting via angiotensin type 1 receptors in the brain, activates the sympathetic nervous system in heart failure (HF)." | 7.74 | Angiotensin II-triggered p44/42 mitogen-activated protein kinase mediates sympathetic excitation in heart failure rats. ( Felder, RB; Wei, SG; Weiss, RM; Yu, Y; Zhang, ZH, 2008) |
| "Angiotensin II (Ang II), acting via angiotensin type 1 receptors in the brain, activates the sympathetic nervous system in heart failure (HF)." | 3.74 | Angiotensin II-triggered p44/42 mitogen-activated protein kinase mediates sympathetic excitation in heart failure rats. ( Felder, RB; Wei, SG; Weiss, RM; Yu, Y; Zhang, ZH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, P | 1 |
| Sun, Y | 1 |
| Yang, J | 1 |
| Chen, S | 1 |
| Liu, AD | 1 |
| Holmberg, L | 1 |
| Huang, X | 1 |
| Tang, C | 1 |
| Du, J | 1 |
| Jin, H | 1 |
| Abdelhamid, G | 1 |
| El-Kadi, AO | 1 |
| Wei, SG | 1 |
| Yu, Y | 1 |
| Zhang, ZH | 1 |
| Weiss, RM | 1 |
| Felder, RB | 1 |
| Adams, V | 2 |
| Linke, A | 2 |
| Wisloff, U | 1 |
| Döring, C | 1 |
| Erbs, S | 1 |
| Kränkel, N | 1 |
| Witt, CC | 1 |
| Labeit, S | 1 |
| Müller-Werdan, U | 1 |
| Schuler, G | 2 |
| Hambrecht, R | 2 |
| Nehrhoff, B | 1 |
| Späte, U | 1 |
| Schulze, PC | 1 |
| Baur, A | 1 |
| Gielen, S | 1 |
5 other studies available for pd 98059 and Cardiac Failure
| Article | Year |
|---|---|
The ERK1/2 signaling pathway is involved in sulfur dioxide preconditioning-induced protection against cardiac dysfunction in isolated perfused rat heart subjected to myocardial ischemia/reperfusion.
Topics: Animals; Cardiotonic Agents; Flavonoids; Heart Failure; Humans; Ischemic Preconditioning; Male; MAP | 2013 |
Buthionine sulfoximine, an inhibitor of glutathione biosynthesis, induces expression of soluble epoxide hydrolase and markers of cellular hypertrophy in a rat cardiomyoblast cell line: roles of the NF-κB and MAPK signaling pathways.
Topics: Animals; Antioxidants; Atrial Natriuretic Factor; Butadienes; Buthionine Sulfoximine; Cardiomegaly; | 2015 |
Angiotensin II-triggered p44/42 mitogen-activated protein kinase mediates sympathetic excitation in heart failure rats.
Topics: Acute Disease; Analysis of Variance; Angiotensin II; Animals; Chronic Disease; Disease Models, Anima | 2008 |
Myocardial expression of Murf-1 and MAFbx after induction of chronic heart failure: Effect on myocardial contractility.
Topics: Animals; Animals, Newborn; Blotting, Western; Echocardiography; Flavonoids; Gene Expression; Heart F | 2007 |
Induction of iNOS expression in skeletal muscle by IL-1beta and NFkappaB activation: an in vitro and in vivo study.
Topics: Aged; Animals; Antioxidants; Blotting, Western; Case-Control Studies; Cytokines; Electrophoretic Mob | 2002 |