pd 98059 has been researched along with Carcinoma, Small Cell in 5 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methadone treatment suggests a novel therapeutic approach for patients presenting 'variant' SCLC and non-SCLC morphologies, since they respond less to conventional therapy." | 1.30 | Effects of bombesin on methadone-induced apoptosis of human lung cancer cells. ( Heusch, WL; Maneckjee, R, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, Z | 1 |
| Gao, F | 1 |
| Flagg, T | 1 |
| Deng, X | 1 |
| Seufferlein, T | 1 |
| Rozengurt, E | 1 |
| Ravi, RK | 1 |
| Weber, E | 1 |
| McMahon, M | 1 |
| Williams, JR | 1 |
| Baylin, S | 1 |
| Mal, A | 1 |
| Harter, ML | 1 |
| Dillehay, LE | 1 |
| Claudio, PP | 1 |
| Giordano, A | 1 |
| Nelkin, BD | 1 |
| Mabry, M | 1 |
| Heusch, WL | 1 |
| Maneckjee, R | 1 |
| Bondzi, C | 1 |
| Litz, J | 1 |
| Dent, P | 1 |
| Krystal, GW | 1 |
5 other studies available for pd 98059 and Carcinoma, Small Cell
| Article | Year |
|---|---|
Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Antineoplastic Agents; Apoptosis; Bungarotoxins; Carcinogen | 2004 |
Galanin, neurotensin, and phorbol esters rapidly stimulate activation of mitogen-activated protein kinase in small cell lung cancer cells.
Topics: Bradykinin; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Carcinoma, Small Cell; Down-R | 1996 |
Activated Raf-1 causes growth arrest in human small cell lung cancer cells.
Topics: Adenovirus E1A Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Small Cell; CDC2 P | 1998 |
Effects of bombesin on methadone-induced apoptosis of human lung cancer cells.
Topics: Apoptosis; Blotting, Western; Bombesin; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Non | 1999 |
Src family kinase activity is required for Kit-mediated mitogen-activated protein (MAP) kinase activation, however loss of functional retinoblastoma protein makes MAP kinase activation unnecessary for growth of small cell lung cancer cells.
Topics: Blotting, Western; Carcinoma, Small Cell; Cell Division; Dose-Response Relationship, Drug; Enzyme Ac | 2000 |