pd 98059 has been researched along with Carcinoma, Lewis Lung in 3 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Carcinoma, Lewis Lung: A carcinoma discovered by Dr. Margaret R. Lewis of the Wistar Institute in 1951. This tumor originated spontaneously as a carcinoma of the lung of a C57BL mouse. The tumor does not appear to be grossly hemorrhagic and the majority of the tumor tissue is a semifirm homogeneous mass. (From Cancer Chemother Rep 2 1972 Nov;(3)1:325) It is also called 3LL and LLC and is used as a transplantable malignancy.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, D | 3 |
| Brodt, P | 3 |
| Tang, Y | 1 |
| Fallavollita, L | 1 |
| Bar-Eli, M | 1 |
| Meloche, S | 1 |
3 other studies available for pd 98059 and Carcinoma, Lewis Lung
| Article | Year |
|---|---|
Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
Topics: Amino Acid Substitution; Androstadienes; Animals; Carcinoma, Lewis Lung; Chromones; Collagen; Drug C | 2003 |
Vascular endothelial growth factor C expression and lymph node metastasis are regulated by the type I insulin-like growth factor receptor.
Topics: Animals; Carcinoma, Lewis Lung; Chromones; Endothelial Growth Factors; Enzyme Inhibitors; Flavonoids | 2003 |
Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals.
Topics: Androstadienes; Animals; Blotting, Western; Carcinoma, Lewis Lung; Cell Line, Tumor; Chloramphenicol | 2004 |