pd 98059 has been researched along with Brain Edema in 5 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (40.00) | 29.6817 |
2010's | 3 (60.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Yuan, J | 1 |
Guo, X | 1 |
Liu, Z | 1 |
Zhao, X | 1 |
Feng, Y | 1 |
Song, S | 2 |
Cui, C | 1 |
Jiang, P | 1 |
Yang, Y | 1 |
Zhang, X | 1 |
Cui, H | 1 |
Zhang, C | 1 |
Zhu, C | 1 |
Li, L | 1 |
Wu, L | 1 |
Miao, S | 1 |
Zou, LB | 1 |
Wu, P | 1 |
Hao, H | 1 |
Tang, K | 1 |
Zeng, P | 1 |
Xiong, J | 1 |
Li, HH | 1 |
Wu, Q | 1 |
Cai, L | 1 |
Ye, DY | 1 |
Qin, Z | 1 |
Xi, G | 2 |
Silbergleit, R | 1 |
Keep, RF | 2 |
Hoff, JT | 2 |
Hua, Y | 2 |
Duong, HK | 1 |
5 other studies available for pd 98059 and Brain Edema
Article | Year |
---|---|
Vitamin D receptor activation influences the ERK pathway and protects against neurological deficits and neuronal death.
Topics: Animals; Apoptosis; Brain Edema; Brain Ischemia; Calcitriol; Flavonoids; MAP Kinase Signaling System | 2018 |
Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways.
Topics: Animals; Apoptosis; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Caspase 3; Chromones; Enzy | 2014 |
Lipoxin A4 inhibits 5-lipoxygenase translocation and leukotrienes biosynthesis to exert a neuroprotective effect in cerebral ischemia/reperfusion injury.
Topics: Animals; Animals, Newborn; Arachidonate 5-Lipoxygenase; Astrocytes; Brain Edema; Brain Ischemia; Dis | 2012 |
Preconditioning with hyperbaric oxygen attenuates brain edema after experimental intracerebral hemorrhage.
Topics: Animals; Brain; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Drug Administration Schedu | 2007 |
Activation of p44/42 mitogen activated protein kinases in thrombin-induced brain tolerance.
Topics: Animals; Basal Ganglia; Brain Edema; Brain Ischemia; Cell Survival; Cerebral Cortex; Cerebral Hemorr | 2001 |