pd 98059 has been researched along with Bone Cancer in 12 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tan, TW | 1 |
| Yang, WH | 1 |
| Lin, YT | 1 |
| Hsu, SF | 1 |
| Li, TM | 1 |
| Kao, ST | 1 |
| Chen, WC | 1 |
| Fong, YC | 1 |
| Tang, CH | 1 |
| Harisi, R | 1 |
| Kenessey, I | 1 |
| Olah, JN | 1 |
| Timar, F | 1 |
| Babo, I | 1 |
| Pogany, G | 1 |
| Paku, S | 1 |
| Jeney, A | 1 |
| Matsuda, T | 1 |
| Kondo, A | 1 |
| Tsunashima, Y | 1 |
| Togari, A | 1 |
| Ibaragi, S | 1 |
| Shimo, T | 1 |
| Iwamoto, M | 1 |
| Hassan, NM | 1 |
| Kodama, S | 1 |
| Isowa, S | 1 |
| Sasaki, A | 1 |
| Healey, JH | 1 |
| Noh, K | 1 |
| Kim, KO | 1 |
| Patel, NR | 1 |
| Staples, JR | 1 |
| Minematsu, H | 1 |
| Nair, K | 1 |
| Lee, FY | 1 |
| Park, H | 1 |
| Drevelle, O | 1 |
| Daviau, A | 1 |
| Senta, H | 1 |
| Bergeron, E | 1 |
| Faucheux, N | 1 |
| Kobayashi, H | 1 |
| Suzuki, M | 1 |
| Kanayama, N | 1 |
| Nishida, T | 1 |
| Takigawa, M | 1 |
| Terao, T | 1 |
| Woessmann, W | 1 |
| Chen, X | 1 |
| Borkhardt, A | 1 |
| Annabi, B | 1 |
| Bouzeghrane, M | 1 |
| Currie, JC | 1 |
| Dulude, H | 1 |
| Daigneault, L | 1 |
| Garde, S | 1 |
| Rabbani, SA | 1 |
| Panchal, C | 1 |
| Wu, JJ | 1 |
| Béliveau, R | 1 |
| Hayashi, C | 1 |
| Rittling, S | 1 |
| Hayata, T | 1 |
| Amagasa, T | 1 |
| Denhardt, D | 1 |
| Ezura, Y | 1 |
| Nakashima, K | 1 |
| Noda, M | 1 |
| Silvany, RE | 1 |
| Eliazer, S | 1 |
| Wolff, NC | 1 |
| Ilaria, RL | 1 |
12 other studies available for pd 98059 and Bone Cancer
| Article | Year |
|---|---|
Cyr61 increases migration and MMP-13 expression via alphavbeta3 integrin, FAK, ERK and AP-1-dependent pathway in human chondrosarcoma cells.
Topics: Bone Neoplasms; Butadienes; Cell Line, Tumor; Cell Movement; Chondrosarcoma; Cysteine-Rich Protein 6 | 2009 |
Differential inhibition of single and cluster type tumor cell migration.
Topics: Adolescent; Bone Neoplasms; Cell Culture Techniques; Cell Movement; Cell Proliferation; Chromones; D | 2009 |
Inhibitory effect of vitamin K(2) on interleukin-1beta-stimulated proliferation of human osteoblasts.
Topics: Adult; Anticoagulants; Bone Neoplasms; Cell Line; Cell Proliferation; Cyclooxygenase 2; Cyclooxygena | 2010 |
Parathyroid hormone-related peptide regulates matrix metalloproteinase-13 gene expression in bone metastatic breast cancer cells.
Topics: Animals; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; D | 2010 |
Commentary on an article by Kyucheol Noh, MD, et al.: "Targeting inflammatory kinase as an adjuvant treatment for osteosarcomas".
Topics: Animals; Apoptosis; Bone Neoplasms; Cell Death; Cell Survival; Doxorubicin; Flavonoids; Humans; Infl | 2011 |
Targeting inflammatory kinase as an adjuvant treatment for osteosarcomas.
Topics: Animals; Apoptosis; Bone Neoplasms; Cell Death; Cell Survival; Doxorubicin; Flavonoids; Flow Cytomet | 2011 |
Preventing MEK1 activation influences the responses of human osteosarcoma cells to bone morphogenetic proteins 2 and 9.
Topics: Amino Acid Sequence; Bone Morphogenetic Protein 2; Bone Neoplasms; Dose-Response Relationship, Drug; | 2013 |
Suppression of urokinase receptor expression by bikunin is associated with inhibition of upstream targets of extracellular signal-regulated kinase-dependent cascade.
Topics: Bone Neoplasms; Butadienes; Carcinoma; Chondrosarcoma; Depression, Chemical; Enzyme Activation; Enzy | 2002 |
Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Butadienes; Cisplatin; Drug Resistance, Neoplasm; | 2002 |
Inhibition of MMP-9 secretion by the anti-metastatic PSP94-derived peptide PCK3145 requires cell surface laminin receptor signaling.
Topics: Antigens, Surface; Bone Neoplasms; Cell Line, Tumor; ELAV Proteins; ELAV-Like Protein 1; Flavonoids; | 2006 |
Serum osteopontin, an enhancer of tumor metastasis to bone, promotes B16 melanoma cell migration.
Topics: 3T3 Cells; Animals; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Flavonoids; | 2007 |
Interference with the constitutive activation of ERK1 and ERK2 impairs EWS/FLI-1-dependent transformation.
Topics: 3T3 Cells; Animals; Binding Sites; Bone Neoplasms; Butadienes; Cell Transformation, Neoplastic; Colo | 2000 |