pd 98059 has been researched along with Body Weight in 7 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the air-puff thresholds (mechanical allodynia), scores of pinprick (mechanical hyperalgesia), and face grooming frequency for acetone application (hypersensitivity for cold stimulation) - 3, 3, 6, 9, 12, 15, 20, 25, 30, and 40 days after surgery." | 1.34 | Intracisternal administration of mitogen-activated protein kinase inhibitors reduced mechanical allodynia following chronic constriction injury of infraorbital nerve in rats. ( Ahn, DK; Han, SR; Jeon, HJ; Ju, JS; Lee, MK; Lim, EJ; Yang, GY, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, C | 1 |
| Zheng, Y | 1 |
| Chen, X | 1 |
| Zhong, X | 1 |
| Zheng, X | 1 |
| Yang, S | 1 |
| Zheng, Z | 1 |
| Fu, C | 1 |
| Li, N | 1 |
| Yuan, Y | 1 |
| Wang, R | 1 |
| Chen, J | 1 |
| Yang, J | 1 |
| Guo, Z | 1 |
| Wang, S | 1 |
| Zhang, Y | 1 |
| Liu, Y | 1 |
| Dong, J | 1 |
| Penna, F | 1 |
| Costamagna, D | 1 |
| Fanzani, A | 1 |
| Bonelli, G | 1 |
| Baccino, FM | 1 |
| Costelli, P | 1 |
| Galuppo, M | 1 |
| Esposito, E | 1 |
| Mazzon, E | 1 |
| Di Paola, R | 1 |
| Paterniti, I | 1 |
| Impellizzeri, D | 1 |
| Cuzzocrea, S | 1 |
| Lee, CK | 1 |
| Kim, J | 1 |
| Won, KJ | 1 |
| Lee, HM | 1 |
| Kim, HJ | 1 |
| Roh, HY | 1 |
| Park, HJ | 1 |
| Shin, HS | 1 |
| Park, TK | 1 |
| Kim, B | 1 |
| Lee, SM | 1 |
| Lim, EJ | 1 |
| Jeon, HJ | 1 |
| Yang, GY | 1 |
| Lee, MK | 1 |
| Ju, JS | 1 |
| Han, SR | 1 |
| Ahn, DK | 1 |
| Collins, AR | 1 |
| Meehan, WP | 1 |
| Kintscher, U | 1 |
| Jackson, S | 1 |
| Wakino, S | 1 |
| Noh, G | 1 |
| Palinski, W | 1 |
| Hsueh, WA | 1 |
| Law, RE | 1 |
7 other studies available for pd 98059 and Body Weight
| Article | Year |
|---|---|
α-NETA down-regulates CMKLR1 mRNA expression in ileum and prevents body weight gains collaborating with ERK inhibitor PD98059 in turn to alleviate hepatic steatosis in HFD-induced obese mice but no impact on ileal mucosal integrity and steatohepatitis pro
Topics: Animals; Body Weight; Diet, High-Fat; Fatty Liver; Ileum; Intestinal Mucosa; Liver; Male; Mice; Mice | 2023 |
Chronic intermittent hypobaric hypoxia provides vascular protection in the aorta of the 2-kidney, 1-clip rat model of hypertension.
Topics: Acetylcholine; Animals; Anthracenes; Aorta; Basic Helix-Loop-Helix Transcription Factors; Blood Pres | 2018 |
Muscle wasting and impaired myogenesis in tumor bearing mice are prevented by ERK inhibition.
Topics: Animals; Blotting, Western; Body Weight; Cell Line; Enzyme-Linked Immunosorbent Assay; Extracellular | 2010 |
MEK inhibition suppresses the development of lung fibrosis in the bleomycin model.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Bleomycin; Body Weight; Butadienes; Fas Ligand Prote | 2011 |
Phorbol ester-induced contraction through p38 mitogen-activated protein kinase is diminished in aortas from DOCA-salt hypertensive rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Desoxycorticosterone; Enzyme Inhibitors; Flav | 2006 |
Intracisternal administration of mitogen-activated protein kinase inhibitors reduced mechanical allodynia following chronic constriction injury of infraorbital nerve in rats.
Topics: Animals; Behavior, Animal; Body Weight; Constriction; Disease Models, Animal; Dose-Response Relation | 2007 |
Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta; Arteriosclerosis; Blood Glu | 2001 |