pd 98059 has been researched along with Blood Pressure, Low in 2 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacological inhibition of RVLM phosphoinositide 3-kinase (PI3K)/Akt (wortmannin), ERK1/2 (PD98059 [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one]), or nNOS (N(ω)-propyl-l-arginine), or activation of adenylyl cyclase (forskolin) virtually abolished intra-RVLM Abn CBD-evoked hypotension and the increases in Akt, ERK1/2, and nNOS phosphorylation and in ADN levels in the RVLM." | 3.80 | Neuronal nitric oxide synthase-dependent elevation in adiponectin in the rostral ventrolateral medulla underlies g protein-coupled receptor 18-mediated hypotension in conscious rats. ( Abdel-Rahman, AA; Penumarti, A, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Penumarti, A | 1 |
| Abdel-Rahman, AA | 1 |
| Schulman, D | 1 |
| Latchman, DS | 1 |
| Yellon, DM | 1 |
2 other studies available for pd 98059 and Blood Pressure, Low
| Article | Year |
|---|---|
Neuronal nitric oxide synthase-dependent elevation in adiponectin in the rostral ventrolateral medulla underlies g protein-coupled receptor 18-mediated hypotension in conscious rats.
Topics: Adenylyl Cyclases; Adiponectin; Androstadienes; Animals; Anisoles; Arginine; Colforsin; Consciousnes | 2014 |
Urocortin protects the heart from reperfusion injury via upregulation of p42/p44 MAPK signaling pathway.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Corticotropin-Releasing Hormone; Enzyme Inhibitors; Fla | 2002 |