pd 98059 has been researched along with Barrett Esophagus in 2 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Barrett Esophagus: A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, X | 1 |
| Li, D | 1 |
| Resnick, MB | 1 |
| Behar, J | 2 |
| Wands, J | 2 |
| Cao, W | 2 |
| Si, J | 1 |
| Beer, DG | 1 |
| Lambeth, D | 1 |
| Chin, YE | 1 |
2 other studies available for pd 98059 and Barrett Esophagus
| Article | Year |
|---|---|
Signaling in H2O2-induced increase in cell proliferation in Barrett's esophageal adenocarcinoma cells.
Topics: Adenocarcinoma; Barrett Esophagus; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Enzyme I | 2011 |
STAT5 mediates PAF-induced NADPH oxidase NOX5-S expression in Barrett's esophageal adenocarcinoma cells.
Topics: Adenocarcinoma; Arachidonic Acids; Barrett Esophagus; Cell Line, Tumor; Enzyme Inhibitors; Esophagea | 2008 |