pd 98059 has been researched along with Atrophy, Muscle in 2 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cachexia affects the majority of cancer patients, with currently no effective treatments." | 1.43 | Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs. ( Barreto, R; Bonetto, A; Gao, H; Liu, Y; Waning, DL; Zimmers, TA, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barreto, R | 1 |
| Waning, DL | 1 |
| Gao, H | 1 |
| Liu, Y | 1 |
| Zimmers, TA | 1 |
| Bonetto, A | 1 |
| Penna, F | 1 |
| Costamagna, D | 1 |
| Fanzani, A | 1 |
| Bonelli, G | 1 |
| Baccino, FM | 1 |
| Costelli, P | 1 |
2 other studies available for pd 98059 and Atrophy, Muscle
| Article | Year |
|---|---|
Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs.
Topics: Activin Receptors, Type II; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Compositio | 2016 |
Muscle wasting and impaired myogenesis in tumor bearing mice are prevented by ERK inhibition.
Topics: Animals; Blotting, Western; Body Weight; Cell Line; Enzyme-Linked Immunosorbent Assay; Extracellular | 2010 |