pd 98059 has been researched along with Atherogenesis in 13 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nifedipine, an L-type calcium channel blocker, protects against the progression of atherosclerosis." | 7.76 | Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice. ( Araki, E; Fukuda, K; Ishii, N; Kawada, T; Kim-Mitsuyama, S; Kinoshita, H; Matsumura, T; Miyamura, N; Motoshima, H; Nakao, S; Nishikawa, T; Senokuchi, T; Takeya, M; Tsutsumi, A, 2010) |
| "Nifedipine, an L-type calcium channel blocker, protects against the progression of atherosclerosis." | 3.76 | Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice. ( Araki, E; Fukuda, K; Ishii, N; Kawada, T; Kim-Mitsuyama, S; Kinoshita, H; Matsumura, T; Miyamura, N; Motoshima, H; Nakao, S; Nishikawa, T; Senokuchi, T; Takeya, M; Tsutsumi, A, 2010) |
| "Atherosclerosis is a chronic inflammatory disease in the vessel." | 1.40 | Aldosterone induces C-reactive protein expression via MR-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells. ( Liu, J; Pang, X; Wang, S; Wu, D; Zhang, X; Zhao, J, 2014) |
| "Also leptin treatment did not alter total tPA concentration or tPA activity in conditioned media." | 1.36 | Leptin upregulates the expression of plasminogen activator inhibitor-1 in human vascular endothelial cells. ( Barber, KR; Hoffmann, M; Jensen, A; Kuniyoshi, FS; Peterson, TE; Shamsuzzaman, AS; Singh, P; Somers, VK, 2010) |
| "We hypothesized a possible mechanism for atherosclerosis in which interleukin-6 (IL-6) might affect the endothelial nitric oxide synthase (eNOS)-caveolin-1 interaction and result in decreased nitric oxide bioavailability in the setting of low-grade inflammation." | 1.36 | Interleukin-6 inhibits endothelial nitric oxide synthase activation and increases endothelial nitric oxide synthase binding to stabilized caveolin-1 in human vascular endothelial cells. ( Cherng, WJ; Hung, MJ; Hung, MY; Pang, JH; Wu, HT, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, P | 1 |
| Tang, LN | 1 |
| Li, GZ | 1 |
| Xu, ZL | 1 |
| Xu, QH | 1 |
| Wang, M | 1 |
| Li, L | 2 |
| Jiang, L | 1 |
| Qiao, Y | 1 |
| Wang, Z | 2 |
| Ma, X | 1 |
| Wang, H | 1 |
| Li, J | 1 |
| Liu, W | 1 |
| Jiang, J | 1 |
| Yan, D | 1 |
| Li, D | 1 |
| Li, W | 1 |
| Ma, Y | 1 |
| Yang, L | 1 |
| Qu, Z | 1 |
| Ruan, Q | 1 |
| Zhang, X | 1 |
| Liu, J | 1 |
| Pang, X | 1 |
| Zhao, J | 1 |
| Wang, S | 1 |
| Wu, D | 1 |
| Zhang, J | 1 |
| Li, B | 1 |
| Gao, X | 1 |
| Liu, Y | 1 |
| Mao, W | 1 |
| Chen, SL | 1 |
| Zhang, L | 1 |
| Chen, Y | 1 |
| Yang, X | 1 |
| Yang, J | 1 |
| Cao, X | 1 |
| Li, X | 1 |
| Miao, QR | 1 |
| Hajjar, DP | 1 |
| Duan, Y | 1 |
| Han, J | 1 |
| Chahine, MN | 1 |
| Blackwood, DP | 1 |
| Dibrov, E | 1 |
| Richard, MN | 1 |
| Pierce, GN | 1 |
| Singh, P | 1 |
| Peterson, TE | 1 |
| Barber, KR | 1 |
| Kuniyoshi, FS | 1 |
| Jensen, A | 1 |
| Hoffmann, M | 1 |
| Shamsuzzaman, AS | 1 |
| Somers, VK | 1 |
| Hung, MJ | 1 |
| Cherng, WJ | 1 |
| Hung, MY | 1 |
| Wu, HT | 1 |
| Pang, JH | 1 |
| Ishii, N | 1 |
| Matsumura, T | 1 |
| Kinoshita, H | 1 |
| Fukuda, K | 1 |
| Motoshima, H | 1 |
| Senokuchi, T | 1 |
| Nakao, S | 1 |
| Tsutsumi, A | 1 |
| Kim-Mitsuyama, S | 1 |
| Kawada, T | 1 |
| Takeya, M | 1 |
| Miyamura, N | 1 |
| Nishikawa, T | 1 |
| Araki, E | 1 |
| Abe, R | 2 |
| Yamashita, N | 1 |
| Rochier, A | 1 |
| Nixon, A | 1 |
| Madri, JA | 1 |
| Sumpio, BE | 1 |
| Miura, S | 1 |
| Matsuo, Y | 1 |
| Kawamura, A | 1 |
| Saku, K | 1 |
| Huang, MS | 1 |
| Morony, S | 1 |
| Lu, J | 1 |
| Zhang, Z | 1 |
| Bezouglaia, O | 1 |
| Tseng, W | 1 |
| Tetradis, S | 1 |
| Demer, LL | 1 |
| Tintut, Y | 1 |
13 other studies available for pd 98059 and Atherogenesis
| Article | Year |
|---|---|
Effects of MiR-21 on the proliferation and migration of vascular smooth muscle cells in rats with atherosclerosis via the Akt/ERK signaling pathway.
Topics: Animals; Atherosclerosis; Cell Movement; Cell Proliferation; Cells, Cultured; Diet, High-Fat; Diseas | 2019 |
Inhibition of microRNA-103 attenuates inflammation and endoplasmic reticulum stress in atherosclerosis through disrupting the PTEN-mediated MAPK signaling.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Disease Models, Animal; Endoplasmic Re | 2020 |
Pentraxin 3 promotes oxLDL uptake and inhibits cholesterol efflux from macrophage-derived foam cells.
Topics: Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; C-Reactive Protein; Cell Li | 2014 |
Aldosterone induces C-reactive protein expression via MR-ROS-MAPK-NF-κB signal pathway in rat vascular smooth muscle cells.
Topics: Aldosterone; Animals; Atherosclerosis; C-Reactive Protein; Flavonoids; Gene Expression Regulation; M | 2014 |
Resveratrol ameliorates low shear stress‑induced oxidative stress by suppressing ERK/eNOS‑Thr495 in endothelial cells.
Topics: Antioxidants; Atherosclerosis; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Flavonoids | 2014 |
MEK1/2 inhibitors activate macrophage ABCG1 expression and reverse cholesterol transport-An anti-atherogenic function of ERK1/2 inhibition.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter, Subfamily G, M | 2016 |
Oxidized LDL affects smooth muscle cell growth through MAPK-mediated actions on nuclear protein import.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Atherosclerosis; Cell Nucleus; Cell Proliferatio | 2009 |
Leptin upregulates the expression of plasminogen activator inhibitor-1 in human vascular endothelial cells.
Topics: Atherosclerosis; Cells, Cultured; Endothelium, Vascular; Flavonoids; Humans; Leptin; Mitogen-Activat | 2010 |
Interleukin-6 inhibits endothelial nitric oxide synthase activation and increases endothelial nitric oxide synthase binding to stabilized caveolin-1 in human vascular endothelial cells.
Topics: Atherosclerosis; Base Sequence; Caveolin 1; Cells, Cultured; Endothelial Cells; Enzyme Activation; E | 2010 |
Nifedipine induces peroxisome proliferator-activated receptor-gamma activation in macrophages and suppresses the progression of atherosclerosis in apolipoprotein E-deficient mice.
Topics: Amlodipine; Animals; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Bin | 2010 |
Pulsatile to-fro flow induces greater and sustained expression of tissue factor RNA in HUVEC than unidirectional laminar flow.
Topics: Atherosclerosis; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Flavonoids; Humans; Imidazol | 2011 |
JTT-705 blocks cell proliferation and angiogenesis through p38 kinase/p27(kip1) and Ras/p21(waf1) pathways.
Topics: Amides; Atherosclerosis; Cell Division; Cells, Cultured; Coronary Vessels; Cyclin-Dependent Kinase I | 2005 |
Atherogenic phospholipids attenuate osteogenic signaling by BMP-2 and parathyroid hormone in osteoblasts.
Topics: Animals; Atherosclerosis; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; DNA-Binding Pro | 2007 |