pd 98059 has been researched along with Arthritis, Degenerative in 10 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prasadam, I | 2 |
| van Gennip, S | 1 |
| Friis, T | 1 |
| Shi, W | 1 |
| Crawford, R | 2 |
| Xiao, Y | 2 |
| Ogura, N | 1 |
| Satoh, K | 1 |
| Akutsu, M | 1 |
| Tobe, M | 1 |
| Kuyama, K | 1 |
| Kuboyama, N | 1 |
| Sakamaki, H | 1 |
| Kujiraoka, H | 1 |
| Kondoh, T | 1 |
| Lee, Y | 1 |
| Pai, M | 1 |
| Brederson, JD | 1 |
| Wilcox, D | 1 |
| Hsieh, G | 1 |
| Jarvis, MF | 1 |
| Bitner, RS | 1 |
| Koskinen, A | 1 |
| Juslin, S | 1 |
| Nieminen, R | 1 |
| Moilanen, T | 2 |
| Vuolteenaho, K | 2 |
| Moilanen, E | 2 |
| Masuko, K | 1 |
| Murata, M | 1 |
| Beppu, M | 1 |
| Nakamura, H | 1 |
| Kato, T | 1 |
| Yudoh, K | 1 |
| Hsieh, MS | 1 |
| Ho, HC | 1 |
| Chou, DT | 1 |
| Pan, S | 1 |
| Liang, YC | 1 |
| Hsieh, TY | 1 |
| Lan, JL | 1 |
| Tsai, SH | 1 |
| Kim, KW | 1 |
| Cho, ML | 1 |
| Park, MK | 1 |
| Yoon, CH | 1 |
| Park, SH | 1 |
| Lee, SH | 1 |
| Kim, HY | 1 |
| Wang, CH | 1 |
| Chen, LN | 1 |
| Zhu, P | 1 |
| Fan, CM | 1 |
| Wang, YH | 1 |
| Jia, JF | 1 |
| Al-Saffar, N | 1 |
| Knowles, RG | 1 |
10 other studies available for pd 98059 and Arthritis, Degenerative
| Article | Year |
|---|---|
ERK-1/2 and p38 in the regulation of hypertrophic changes of normal articular cartilage chondrocytes induced by osteoarthritic subchondral osteoblasts.
Topics: Adult; Aged; Alkaline Phosphatase; Cartilage, Articular; Cell Communication; Cell Differentiation; C | 2010 |
MCP-1 production in temporomandibular joint inflammation.
Topics: Adolescent; Adult; Animals; Anthracenes; Autoantigens; Calcium-Calmodulin-Dependent Protein Kinases; | 2010 |
Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord.
Topics: Animals; Behavior, Animal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Hyperalgesia; Imm | 2011 |
Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways.
Topics: Adiponectin; Aged; Biomarkers; Blotting, Western; Cartilage; Cartilage Oligomeric Matrix Protein; Ce | 2011 |
Aggravation of ADAMTS and matrix metalloproteinase production and role of ERK1/2 pathway in the interaction of osteoarthritic subchondral bone osteoblasts and articular cartilage chondrocytes -- possible pathogenic role in osteoarthritis.
Topics: ADAM Proteins; ADAMTS4 Protein; ADAMTS5 Protein; Cartilage, Articular; Cell Communication; Cells, Cu | 2012 |
Sphingosine-1-phosphate modulates expression of vascular endothelial growth factor in human articular chondrocytes: a possible new role in arthritis.
Topics: Aged; Cartilage, Articular; Cells, Cultured; Chondrocytes; Drug Interactions; Enzyme Inhibitors; Fem | 2012 |
Expression of matrix metalloproteinase-9 (gelatinase B) in gouty arthritis and stimulation of MMP-9 by urate crystals in macrophages.
Topics: Animals; Arthritis, Gouty; Arthritis, Rheumatoid; Blotting, Western; Enzyme Inhibitors; Enzyme Precu | 2003 |
Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor kappaB-dependent pathway in patients with rheumatoid arthritis.
Topics: Adult; Aged; Androstadienes; Antibodies, Monoclonal; Arthritis, Rheumatoid; CD28 Antigens; CD3 Compl | 2005 |
[CD147 stimulates the angiogenesis in rheumatoid synovium via the activation of vascular endothelial growth factor].
Topics: Adult; Aged; Anthracenes; Arthritis, Rheumatoid; Basigin; Calcium-Calmodulin-Dependent Protein Kinas | 2007 |
Regulation of the nitric oxide production resulting from the glucocorticoid-insensitive expression of iNOS in human osteoarthritic cartilage.
Topics: Analysis of Variance; Cartilage, Articular; Cell Culture Techniques; Dexamethasone; Dose-Response Re | 2001 |