Page last updated: 2024-11-02

pd 98059 and Arteriosclerosis

pd 98059 has been researched along with Arteriosclerosis in 15 studies

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.

Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's15 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gennaro, G1
Ménard, C1
Giasson, E1
Michaud, SE1
Palasis, M1
Meloche, S1
Rivard, A1
Huber, J1
Bochkov, VN1
Binder, BR1
Leitinger, N1
Sugawara, A1
Takeuchi, K1
Uruno, A1
Kudo, M1
Sato, K1
Ito, S1
Harja, E1
Bucciarelli, LG1
Lu, Y1
Stern, DM1
Zou, YS1
Schmidt, AM1
Yan, SF1
Li, L1
Sawamura, T1
Renier, G1
Lin, SJ1
Shyue, SK1
Hung, YY1
Chen, YH1
Ku, HH1
Chen, JW1
Tam, KB1
Chen, YL1
Peng, CY1
Pan, SL1
Guh, JH1
Liu, YN1
Chang, YL1
Kuo, SC1
Lee, FY1
Teng, CM1
Shin, HJ1
Oh, J1
Kang, SM1
Lee, JH1
Shin, MJ1
Hwang, KC1
Jang, Y1
Chung, JH1
Huang, Y1
Fleming, AJ1
Wu, S1
Virella, G1
Lopes-Virella, MF1
Brizzi, MF1
Formato, L1
Dentelli, P1
Rosso, A1
Pavan, M1
Garbarino, G1
Pegoraro, M1
Camussi, G1
Pegoraro, L1
Collins, AR1
Meehan, WP2
Kintscher, U2
Jackson, S1
Wakino, S1
Noh, G1
Palinski, W1
Hsueh, WA2
Law, RE2
Weiss, RH1
Howard, LL1
Goetze, S1
Kaneshiro, K1
Collins, A1
Fleck, E1
Hernández, M1
Fuentes, L1
Fernández Avilés, FJ1
Crespo, MS1
Nieto, ML1
Watanabe, T1
Pakala, R1
Katagiri, T1
Benedict, CR1

Other Studies

15 other studies available for pd 98059 and Arteriosclerosis

ArticleYear
Role of p44/p42 MAP kinase in the age-dependent increase in vascular smooth muscle cell proliferation and neointimal formation.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Feb-01, Volume: 23, Issue:2

    Topics: Age Factors; Aging; Animals; Aorta; Apoptosis; Arteriosclerosis; Catheterization; Cell Division; Cel

2003
The isoprostane 8-iso-PGE2 stimulates endothelial cells to bind monocytes via cyclic AMP- and p38 MAP kinase-dependent signaling pathways.
    Antioxidants & redox signaling, 2003, Volume: 5, Issue:2

    Topics: Arteriosclerosis; Blotting, Western; Cell Adhesion; Cell Communication; Cells, Cultured; Coculture T

2003
Effects of mitogen-activated protein kinase pathway and co-activator CREP-binding protein on peroxisome proliferator-activated receptor-gamma-mediated transcription suppression of angiotensin II type 1 receptor gene.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:8

    Topics: Animals; Arteriosclerosis; Cells, Cultured; CREB-Binding Protein; Enzyme Inhibitors; Flavonoids; MAP

2003
Early growth response-1 promotes atherogenesis: mice deficient in early growth response-1 and apolipoprotein E display decreased atherosclerosis and vascular inflammation.
    Circulation research, 2004, Feb-20, Volume: 94, Issue:3

    Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Blood Glucose; Calcium-Calmodulin-Dependent Pro

2004
Glucose enhances human macrophage LOX-1 expression: role for LOX-1 in glucose-induced macrophage foam cell formation.
    Circulation research, 2004, Apr-16, Volume: 94, Issue:7

    Topics: Acetylcysteine; Adult; Aged; Anti-Infective Agents; Antioxidants; Arteriosclerosis; Cells, Cultured;

2004
Superoxide dismutase inhibits the expression of vascular cell adhesion molecule-1 and intracellular cell adhesion molecule-1 induced by tumor necrosis factor-alpha in human endothelial cells through the JNK/p38 pathways.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:2

    Topics: Anthracenes; Aorta; Arteriosclerosis; Cell Adhesion; Depression, Chemical; Endothelial Cells; Endoth

2005
The indazole derivative YD-3 inhibits thrombin-induced vascular smooth muscle cell proliferation and attenuates intimal thickening after balloon injury.
    Thrombosis and haemostasis, 2004, Volume: 92, Issue:6

    Topics: Administration, Oral; Animals; Aorta, Thoracic; Arteriosclerosis; Blotting, Western; Catheterization

2004
Leptin induces hypertrophy via p38 mitogen-activated protein kinase in rat vascular smooth muscle cells.
    Biochemical and biophysical research communications, 2005, Apr-01, Volume: 329, Issue:1

    Topics: Animals; Anthracenes; Aorta; Arteriosclerosis; Blotting, Western; Cells, Cultured; DNA; DNA-Binding

2005
Fc-gamma receptor cross-linking by immune complexes induces matrix metalloproteinase-1 in U937 cells via mitogen-activated protein kinase.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:12

    Topics: Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antigen-Antibody Complex; Antigens, CD; Arterios

2000
Interleukin-3 stimulates migration and proliferation of vascular smooth muscle cells: a potential role in atherogenesis.
    Circulation, 2001, Jan-30, Volume: 103, Issue:4

    Topics: Arteriosclerosis; Blotting, Northern; Cell Division; Cell Movement; Cells, Cultured; DNA; Endothelia

2001
Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2001, Volume: 21, Issue:3

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta; Arteriosclerosis; Blood Glu

2001
p73 is a growth-regulated protein in vascular smooth muscle cells and is present at high levels in human atherosclerotic plaque.
    Cellular signalling, 2001, Volume: 13, Issue:10

    Topics: Arteriosclerosis; Becaplermin; Benzoquinones; Cell Line; Culture Media; DNA-Binding Proteins; Enzyme

2001
TNFalpha induces expression of transcription factors c-fos, Egr-1, and Ets-1 in vascular lesions through extracellular signal-regulated kinases 1/2.
    Atherosclerosis, 2001, Volume: 159, Issue:1

    Topics: Animals; Arteriosclerosis; Blotting, Western; Cells, Cultured; DNA-Binding Proteins; Early Growth Re

2001
Secretory phospholipase A(2) elicits proinflammatory changes and upregulates the surface expression of fas ligand in monocytic cells: potential relevance for atherogenesis.
    Circulation research, 2002, Jan-11, Volume: 90, Issue:1

    Topics: Arteriosclerosis; Cell Line; Chemokine CCL2; Cyclooxygenase 2; Enzyme Activation; Fas Ligand Protein

2002
Oxidized low-density lipoproteins potentiate the mitogenic effect of 5-hydroxytryptamine on vascular smooth muscle cells.
    Japanese heart journal, 2002, Volume: 43, Issue:1

    Topics: Animals; Arteriosclerosis; Cell Division; Flavonoids; Humans; Lipoproteins, LDL; Male; Mitogens; Mus

2002