pd 98059 has been researched along with Airflow Obstruction, Chronic in 2 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A major feature of chronic obstructive pulmonary disease (COPD) is airway remodelling, which includes an increased airway smooth muscle (ASM) mass." | 1.36 | Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype. ( Gosens, R; Lesterhuis, AH; Meurs, H; Pera, T; Sami, R; van der Toorn, M; Zaagsma, J, 2010) |
| "The LTB4 concentrations were higher in COPD than in controls (P < 0." | 1.33 | Muscarinic receptors, leukotriene B4 production and neutrophilic inflammation in COPD patients. ( Bonanno, A; Bonsignore, G; Bousquet, J; Giorgi, RD; Gjomarkaj, M; Mirabella, F; Profita, M; Riccobono, L; Sala, A; Vignola, AM, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pera, T | 1 |
| Gosens, R | 1 |
| Lesterhuis, AH | 1 |
| Sami, R | 1 |
| van der Toorn, M | 1 |
| Zaagsma, J | 1 |
| Meurs, H | 1 |
| Profita, M | 1 |
| Giorgi, RD | 1 |
| Sala, A | 1 |
| Bonanno, A | 1 |
| Riccobono, L | 1 |
| Mirabella, F | 1 |
| Gjomarkaj, M | 1 |
| Bonsignore, G | 1 |
| Bousquet, J | 1 |
| Vignola, AM | 1 |
2 other studies available for pd 98059 and Airflow Obstruction, Chronic
| Article | Year |
|---|---|
Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype.
Topics: Airway Remodeling; Animals; Cattle; Cell Proliferation; Cells, Cultured; Cyclin D1; DNA Replication; | 2010 |
Muscarinic receptors, leukotriene B4 production and neutrophilic inflammation in COPD patients.
Topics: Acetylcholine; Aged; Calcium-Binding Proteins; Cells, Cultured; Chemotaxis, Leukocyte; Female; Flavo | 2005 |