pd 98059 has been researched along with Adenocarcinoma, Basal Cell in 50 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present evidence that pyrrolidine dithiocarbamate (PDTC) inhibits growth of p53-negative pancreatic adenocarcinoma cell lines via cell cycle arrest in the S-phase, while it has no effect on primary fibroblast proliferation." | 7.73 | Increased stability of P21(WAF1/CIP1) mRNA is required for ROS/ERK-dependent pancreatic adenocarcinoma cell growth inhibition by pyrrolidine dithiocarbamate. ( Costanzo, C; Dalla Pozza, E; Donadelli, M; Palmieri, M; Piacentini, P; Scarpa, A; Scupoli, MT, 2006) |
| " In this study, we chose human colorectal adenocarcinoma cell line HT-29 as the experimental model, and investigated the differential biological effects between 250 mGy single dose LDIR and 250 mGy intermittent LDIR pretreatments in high dose irradiation (HDIR) radiotherapy and 5-fluorouracil (5-FU) based chemotherapy." | 3.85 | Intermittent low dose irradiation enhances the effectiveness of radio- and chemo-therapy for human colorectal adenocarcinoma cell line HT-29. ( Li, Y; Wang, Y; Yang, L; Yin, D, 2017) |
| "We present evidence that pyrrolidine dithiocarbamate (PDTC) inhibits growth of p53-negative pancreatic adenocarcinoma cell lines via cell cycle arrest in the S-phase, while it has no effect on primary fibroblast proliferation." | 3.73 | Increased stability of P21(WAF1/CIP1) mRNA is required for ROS/ERK-dependent pancreatic adenocarcinoma cell growth inhibition by pyrrolidine dithiocarbamate. ( Costanzo, C; Dalla Pozza, E; Donadelli, M; Palmieri, M; Piacentini, P; Scarpa, A; Scupoli, MT, 2006) |
| "In this study we have investigated the role of mitogen-induced and stress-activated MAP kinase pathways in the cellular response to taxol, etoposide and ceramide in three different human cancer cell lines: HeLa cervical carcinoma, MCF7 breast cancer and A431 squamous carcinoma cells." | 3.71 | The role of MAPK pathways in the action of chemotherapeutic drugs. ( Boldt, S; Kolch, W; Weidle, UH, 2002) |
| "We treated 7 ovarian cancer cell lines with CDDP alone or with CDDP and either a PI3K inhibitor (LY294002), a MEK inhibitor (PD98059), or a MEK/ERK activator (phorbol 12-myristate 13-acetate [PMA]) and assessed cell viability, expression of MEK/ERK and PI3K/Akt, cell cycle distribution, and apoptosis." | 1.38 | Activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathway overcomes cisplatin resistance in ovarian carcinoma cells. ( Harada, T; Itamochi, H; Kawaguchi, W; Kigawa, J; Kudoh, A; Naniwa, J; Nonaka, M; Oishi, T; Sato, S; Shimada, M; Terakawa, N; Uegaki, K, 2012) |
| "However, a direct role for leptin in endometrial cancer has not been demonstrated." | 1.37 | Leptin activates STAT3 and ERK1/2 pathways and induces endometrial cancer cell proliferation. ( Gong, C; Liu, Y; Lv, L; Sheng, H; Wang, D; Xiao, W; Yin, J, 2011) |
| "ClC plays an important role in ovarian cancer cell migration." | 1.37 | Effect of a chloride channel inhibitor, 5-nitro-2-(3-phenylpropylamino)-benzoate, on ovarian cancer cell migration. ( Gao, J; Li, S; Yu, Z; Zhang, ZX, 2011) |
| "We have previously demonstrated that in pancreatic cancer ErbB3 is the preferred dimerization partner of EGFR, ErbB3 protein expression level directly correlates with the anti-proliferative effect of erlotinib (an EGFR-specific tyrosine kinase inhibitor), and transient knockdown of ErbB3 expression results in acquired resistance to EGFR-targeted therapy." | 1.36 | ErbB3 expression promotes tumorigenesis in pancreatic adenocarcinoma. ( Arnoletti, JP; Frolov, A; Heslin, MJ; Howard, JH; Kossenkov, AV; Kulesza, P; Liles, JS; Tzeng, CW, 2010) |
| "Metastatic breast cancer cells frequently and ectopically express the transcription factor RUNX2, which normally attenuates proliferation and promotes maturation of osteoblasts." | 1.36 | Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility. ( Cool, SM; Dobson, JR; Goh, X; Ito, Y; Kwok, HS; Leong, DT; Lian, JB; Lim, J; Nathan, SS; Pereira, BP; Pratap, J; Salto-Tellez, M; Stein, GS; van Wijnen, AJ; Voorhoeve, PM, 2010) |
| "Our results demonstrated that in human gastric cancer cells, IL-1beta upregulates the COX-2 gene expression through the activation of MEK/p44/42 and p38 MAP kinases pathway." | 1.31 | Interleukin-1beta induces cyclo-oxygenase-2 expression in gastric cancer cells by the p38 and p44/42 mitogen-activated protein kinase signaling pathways. ( Cho, CH; Fan, XM; Kung, HF; Lam, SK; Lin, MC; Wang, WP; Wong, BC, 2001) |
| "Treatment with cycloheximide resulted in inhibition of cisplatin-induced ERK1/2 activation, demonstrating that ERK1/2 activity induced by cisplatin was dependent on de novo protein synthesis." | 1.30 | Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin. ( Cui, W; Pelling, JC; Persons, DL; Yazlovitskaya, EM, 1999) |
| "Treatment of androgen responsive prostate cancer cells with dihydrotestosterone leads to a rapid and reversible activation of mitogen-activated protein kinases MAPKs (also called extracellular signal-regulated kinases or Erks)." | 1.30 | Rapid signalling by androgen receptor in prostate cancer cells. ( Becker, M; Cato, AC; Klocker, H; Mink, S; Peterziel, H; Schonert, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (12.00) | 18.2507 |
| 2000's | 30 (60.00) | 29.6817 |
| 2010's | 14 (28.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 2 |
| Li, Y | 1 |
| Yang, L | 2 |
| Yin, D | 1 |
| Lee, KH | 1 |
| Koh, SA | 1 |
| Kim, JR | 1 |
| Qian, C | 1 |
| Yao, J | 1 |
| Wang, J | 1 |
| Wang, L | 2 |
| Xue, M | 1 |
| Zhou, T | 1 |
| Liu, W | 2 |
| Si, J | 2 |
| Su, T | 1 |
| Lv, D | 1 |
| Xie, F | 1 |
| Cao, J | 1 |
| Sheikh, IA | 1 |
| Qin, X | 1 |
| Li, L | 1 |
| Chen, L | 1 |
| Fong, YC | 1 |
| Liu, SC | 1 |
| Huang, CY | 1 |
| Li, TM | 1 |
| Hsu, SF | 1 |
| Kao, ST | 1 |
| Tsai, FJ | 1 |
| Chen, WC | 1 |
| Chen, CY | 1 |
| Tang, CH | 1 |
| Han, YH | 1 |
| Park, WH | 1 |
| Liles, JS | 1 |
| Arnoletti, JP | 1 |
| Tzeng, CW | 1 |
| Howard, JH | 1 |
| Kossenkov, AV | 1 |
| Kulesza, P | 1 |
| Heslin, MJ | 1 |
| Frolov, A | 1 |
| Leong, DT | 1 |
| Lim, J | 1 |
| Goh, X | 1 |
| Pratap, J | 1 |
| Pereira, BP | 1 |
| Kwok, HS | 1 |
| Nathan, SS | 1 |
| Dobson, JR | 1 |
| Lian, JB | 1 |
| Ito, Y | 1 |
| Voorhoeve, PM | 1 |
| Stein, GS | 1 |
| Salto-Tellez, M | 1 |
| Cool, SM | 1 |
| van Wijnen, AJ | 1 |
| Lu, J | 1 |
| Liu, K | 1 |
| Zhao, J | 2 |
| Ma, J | 1 |
| Yang, H | 1 |
| Huang, Y | 1 |
| Qin, Z | 1 |
| Bai, R | 1 |
| Jiang, L | 1 |
| Lv, F | 1 |
| Li, P | 1 |
| Yan, W | 1 |
| Zhao, M | 1 |
| Dong, Z | 1 |
| Liu, Y | 1 |
| Lv, L | 1 |
| Xiao, W | 1 |
| Gong, C | 1 |
| Yin, J | 1 |
| Wang, D | 1 |
| Sheng, H | 1 |
| Amin, S | 1 |
| Kumar, A | 1 |
| Nilchi, L | 1 |
| Wright, K | 1 |
| Kozlowski, M | 1 |
| Zhou, X | 1 |
| Li, D | 1 |
| Resnick, MB | 1 |
| Behar, J | 2 |
| Wands, J | 2 |
| Cao, W | 2 |
| Yu, Z | 1 |
| Zhang, ZX | 1 |
| Li, S | 1 |
| Gao, J | 1 |
| Nonaka, M | 1 |
| Itamochi, H | 1 |
| Kawaguchi, W | 1 |
| Kudoh, A | 1 |
| Sato, S | 2 |
| Uegaki, K | 1 |
| Naniwa, J | 1 |
| Shimada, M | 1 |
| Oishi, T | 1 |
| Terakawa, N | 1 |
| Kigawa, J | 1 |
| Harada, T | 1 |
| Chen, HW | 1 |
| Chao, CY | 1 |
| Lin, LL | 1 |
| Lu, CY | 1 |
| Liu, KL | 1 |
| Lii, CK | 1 |
| Li, CC | 1 |
| Lin, SY | 1 |
| Liang, YC | 1 |
| Ho, YS | 1 |
| Tsai, SH | 1 |
| Pan, S | 1 |
| Lee, WS | 1 |
| Kodama, Y | 1 |
| Baxter, RC | 1 |
| Martin, JL | 1 |
| Boldt, S | 1 |
| Weidle, UH | 1 |
| Kolch, W | 1 |
| Beum, PV | 1 |
| Bastola, DR | 1 |
| Cheng, PW | 1 |
| Tyagi, A | 1 |
| Agarwal, R | 1 |
| Agarwal, C | 1 |
| Yacoub, A | 1 |
| McKinstry, R | 1 |
| Hinman, D | 1 |
| Chung, T | 1 |
| Dent, P | 1 |
| Hagan, MP | 1 |
| Denkert, C | 1 |
| Koch, I | 1 |
| Berger, S | 1 |
| Köbel, M | 1 |
| Siegert, A | 1 |
| Hauptmann, S | 1 |
| Leong, H | 1 |
| Riby, JE | 1 |
| Firestone, GL | 1 |
| Bjeldanes, LF | 1 |
| Zhao, Y | 1 |
| You, H | 1 |
| Yang, Y | 1 |
| Wei, L | 1 |
| Zhang, X | 1 |
| Yao, L | 1 |
| Fan, D | 1 |
| Yu, Q | 1 |
| Wei, SQ | 1 |
| Sui, LH | 1 |
| Zheng, JH | 1 |
| Zhang, GM | 1 |
| Kao, YL | 1 |
| Kang, W | 1 |
| Nielsen, O | 1 |
| Fenger, C | 1 |
| Leslie, G | 1 |
| Holmskov, U | 1 |
| Reid, KB | 1 |
| Ebert, B | 1 |
| Seidel, A | 1 |
| Lampen, A | 1 |
| Coltella, N | 1 |
| Rasola, A | 1 |
| Nano, E | 1 |
| Bardella, C | 1 |
| Fassetta, M | 1 |
| Filigheddu, N | 1 |
| Graziani, A | 1 |
| Comoglio, PM | 1 |
| Di Renzo, MF | 1 |
| Sarinella, F | 1 |
| Calistri, A | 1 |
| Sette, P | 1 |
| Palù, G | 1 |
| Parolin, C | 1 |
| Suthiphongchai, T | 1 |
| Phimsen, S | 1 |
| Sakulkhu, U | 1 |
| Tohtong, R | 1 |
| Uemura, Y | 1 |
| Kobayashi, M | 1 |
| Nakata, H | 1 |
| Kubota, T | 1 |
| Bandobashi, K | 1 |
| Saito, T | 1 |
| Taguchi, H | 1 |
| Donadelli, M | 1 |
| Dalla Pozza, E | 1 |
| Costanzo, C | 1 |
| Scupoli, MT | 1 |
| Piacentini, P | 1 |
| Scarpa, A | 1 |
| Palmieri, M | 1 |
| Chen, YC | 1 |
| Li, JY | 1 |
| Xu, WR | 1 |
| Zhang, YL | 1 |
| Deng, H | 1 |
| Ravikumar, TS | 1 |
| Yang, WL | 1 |
| Beer, DG | 1 |
| Lambeth, D | 1 |
| Chin, YE | 1 |
| Merchant, JL | 2 |
| Du, M | 1 |
| Todisco, A | 2 |
| Yazlovitskaya, EM | 2 |
| Pelling, JC | 2 |
| Persons, DL | 2 |
| Cui, W | 1 |
| Asslan, R | 1 |
| Pradines, A | 1 |
| Pratx, C | 1 |
| Allal, C | 1 |
| Favre, G | 1 |
| Le Gaillard, F | 1 |
| Peterziel, H | 1 |
| Mink, S | 1 |
| Schonert, A | 1 |
| Becker, M | 1 |
| Klocker, H | 1 |
| Cato, AC | 1 |
| Munir, I | 2 |
| Fukunaga, K | 2 |
| Miyazaki, K | 2 |
| Okamura, H | 2 |
| Miyamoto, E | 2 |
| Lobenhofer, EK | 1 |
| Huper, G | 1 |
| Iglehart, JD | 1 |
| Marks, JR | 1 |
| Qiao, D | 1 |
| Chen, W | 1 |
| Stratagoules, ED | 1 |
| Martinez, JD | 1 |
| Chuang, SM | 1 |
| Liou, GY | 1 |
| Yang, JL | 1 |
| Kanasaki, H | 1 |
| Ohba, T | 1 |
| Awasthi, V | 1 |
| King, RJ | 1 |
| Fan, XM | 1 |
| Wong, BC | 1 |
| Lin, MC | 1 |
| Cho, CH | 1 |
| Wang, WP | 1 |
| Kung, HF | 1 |
| Lam, SK | 1 |
| Suzuki, T | 1 |
| Grand, E | 1 |
| Bowman, C | 1 |
| Del Valle, J | 1 |
| Venkateswarlu, S | 1 |
| Dawson, DM | 1 |
| St Clair, P | 1 |
| Gupta, A | 1 |
| Willson, JK | 1 |
| Brattain, MG | 1 |
| Métivier, R | 1 |
| Gay, FA | 1 |
| Hübner, MR | 1 |
| Flouriot, G | 1 |
| Salbert, G | 1 |
| Gannon, F | 1 |
| Kah, O | 1 |
| Pakdel, F | 1 |
50 other studies available for pd 98059 and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Intermittent low dose irradiation enhances the effectiveness of radio- and chemo-therapy for human colorectal adenocarcinoma cell line HT-29.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Benzothiazo | 2017 |
Hepatocyte growth factor-mediated gastrin-releasing peptide induces IL-8 expression through Ets-1 in gastric cancer cells.
Topics: Adenocarcinoma; Base Sequence; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Flavono | 2013 |
ERK1/2 inhibition enhances apoptosis induced by JAK2 silencing in human gastric cancer SGC7901 cells.
Topics: Adenocarcinoma; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Female; Flavonoids; G2 Pha | 2014 |
ERK1/2 mediates lung adenocarcinoma cell proliferation and autophagy induced by apelin-13.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Cyc | 2014 |
Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway.
Topics: Adenocarcinoma; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Cell Movement; Chrom | 2009 |
Treatment with p38 inhibitor partially prevents Calu-6 lung cancer cell death by a proteasome inhibitor, MG132.
Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cyc | 2010 |
ErbB3 expression promotes tumorigenesis in pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromones; Dose-Re | 2010 |
Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility.
Topics: Adenocarcinoma; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Prolifera | 2010 |
VEGF-A not Ang2 mediates endothelial-like differentiation of immature DCs by ERK1/2 signaling in the microenvironment of human colon adenocarcinoma.
Topics: Adenocarcinoma; Angiopoietin-2; Cell Differentiation; Cells, Cultured; Colonic Neoplasms; Culture Me | 2011 |
Leptin activates STAT3 and ERK1/2 pathways and induces endometrial cancer cell proliferation.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Endometrial Neoplasms; Enzyme Inhibitors; Fema | 2011 |
Breast cancer cells proliferation is regulated by tyrosine phosphatase SHP1 through c-jun N-terminal kinase and cooperative induction of RFX-1 and AP-4 transcription factors.
Topics: Adaptor Protein Complex 4; Adenocarcinoma; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Cell P | 2011 |
Signaling in H2O2-induced increase in cell proliferation in Barrett's esophageal adenocarcinoma cells.
Topics: Adenocarcinoma; Barrett Esophagus; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Enzyme I | 2011 |
Effect of a chloride channel inhibitor, 5-nitro-2-(3-phenylpropylamino)-benzoate, on ovarian cancer cell migration.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Cell Line, Tumor; Cell Movement; Chloride Channels; Culture | 2011 |
Activation of the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathway overcomes cisplatin resistance in ovarian carcinoma cells.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Chromones; Cisplatin; | 2012 |
Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells.
Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Carcinogens; Cell Movement; | 2013 |
Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells.
Topics: Adenocarcinoma; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Chromosome Mapping; Colonic Neoplasms | 2002 |
Insulin-like growth factor-I inhibits cell growth in the a549 non-small lung cancer cell line.
Topics: Adenocarcinoma; Apoptosis; Cell Division; Chromones; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; | 2002 |
The role of MAPK pathways in the action of chemotherapeutic drugs.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma, Squamous Cell; Cell C | 2002 |
Mucin biosynthesis: epidermal growth factor downregulates core 2 enzymes in a human airway adenocarcinoma cell line.
Topics: Adenocarcinoma; Carbohydrate Sequence; Down-Regulation; Enzyme Inhibitors; Epidermal Growth Factor; | 2003 |
Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adenocarcinoma; Anthrac | 2003 |
Epidermal growth factor and ionizing radiation up-regulate the DNA repair genes XRCC1 and ERCC1 in DU145 and LNCaP prostate carcinoma through MAPK signaling.
Topics: Adenocarcinoma; Autocrine Communication; Cobalt Radioisotopes; DNA Damage; DNA Repair; DNA-Binding P | 2003 |
Cytokine-suppressive anti-inflammatory drugs (CSAIDs) inhibit invasion and MMP-1 production of ovarian carcinoma cells.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Collagen; Cytokines; Drug Combinations; Enz | 2003 |
Potent ligand-independent estrogen receptor activation by 3,3'-diindolylmethane is mediated by cross talk between the protein kinase A and mitogen-activated protein kinase signaling pathways.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dep | 2004 |
Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Annexin A5; Apoptosis; Blotting, Western; Carrier Proteins; Caspases; Cell Line, Tum | 2004 |
Role of ERK1/2 kinase in cisplatin-induced apoptosis in human ovarian carcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cisplatin; Enzyme | 2004 |
Induction of DMBT1 expression by reduced ERK activity during a gastric mucosa differentiation-like process and its association with human gastric cancer.
Topics: Adenocarcinoma; Agglutinins; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Differentiation; Ce | 2005 |
Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists.
Topics: Adenocarcinoma; Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; AT | 2005 |
p38 MAPK turns hepatocyte growth factor to a death signal that commits ovarian cancer cells to chemotherapy-induced apoptosis.
Topics: Adenocarcinoma; Annexin A5; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tu | 2006 |
Oncolysis of pancreatic tumour cells by a gamma34.5-deleted HSV-1 does not rely upon Ras-activation, but on the PI 3-kinase pathway.
Topics: Adenocarcinoma; Cell Line, Tumor; Chromones; Flavonoids; Gene Deletion; Genes, ras; Genetic Therapy; | 2006 |
PD98059-inhibited invasion of Dunning rat prostate cancer cells involves suppression of motility but not MMP-2 or uPA secretion.
Topics: Adenocarcinoma; Animals; Cell Adhesion; Cell Line, Tumor; Cell Movement; Extracellular Matrix; Extra | 2006 |
Effects of GM-CSF and M-CSF on tumor progression of lung cancer: roles of MEK1/ERK and AKT/PKB pathways.
Topics: Adenocarcinoma; Cell Death; Cell Line, Tumor; Chromones; Disease Progression; Enzyme Activation; Ext | 2006 |
Increased stability of P21(WAF1/CIP1) mRNA is required for ROS/ERK-dependent pancreatic adenocarcinoma cell growth inhibition by pyrrolidine dithiocarbamate.
Topics: Acetylcysteine; Adenocarcinoma; Animals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-De | 2006 |
H pylori stimulates proliferation of gastric cancer cells through activating mitogen-activated protein kinase cascade.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Enzyme Inhibitors; Epitheli | 2006 |
Bone morphogenetic protein-4 inhibits heat-induced apoptosis by modulating MAPK pathways in human colon cancer HCT116 cells.
Topics: Adenocarcinoma; Apoptosis; bcl-2-Associated X Protein; Bone Morphogenetic Protein 4; Bone Morphogene | 2007 |
STAT5 mediates PAF-induced NADPH oxidase NOX5-S expression in Barrett's esophageal adenocarcinoma cells.
Topics: Adenocarcinoma; Arachidonic Acids; Barrett Esophagus; Cell Line, Tumor; Enzyme Inhibitors; Esophagea | 2008 |
Sp1 phosphorylation by Erk 2 stimulates DNA binding.
Topics: Adenocarcinoma; Base Sequence; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme I | 1999 |
Association of apoptosis with the inhibition of extracellular signal-regulated protein kinase activity in the tumor necrosis factor alpha-resistant ovarian carcinoma cell line UCI 101.
Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Div | 1999 |
Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin.
Topics: Adenocarcinoma; Antineoplastic Agents; Calcium-Calmodulin-Dependent Protein Kinases; Cisplatin; Cycl | 1999 |
Epidermal growth factor stimulates 3-hydroxy-3-methylglutaryl-coenzyme A reductase expression via the ErbB-2 pathway in human breast adenocarcinoma cells.
Topics: Adenocarcinoma; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Epidermal | 1999 |
Rapid signalling by androgen receptor in prostate cancer cells.
Topics: Adenocarcinoma; Androgen Antagonists; Cell Nucleus; Cytoplasm; Dihydrotestosterone; DNA-Binding Prot | 1999 |
Mitogen-activated protein kinase activation and regulation of cyclooxygenase 2 expression by platelet-activating factor and hCG in human endometrial adenocarcinoma cell line HEC-1B.
Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents, Hormonal; Chorionic Gonadotropin; Cyclic AMP; | 1999 |
Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis.
Topics: Adenocarcinoma; Androstadienes; Breast Neoplasms; Butadienes; Chromones; Culture Media, Serum-Free; | 2000 |
Bile acid-induced activation of activator protein-1 requires both extracellular signal-regulated kinase and protein kinase C signaling.
Topics: Adenocarcinoma; CCAAT-Enhancer-Binding Proteins; Chloramphenicol O-Acetyltransferase; Deoxycholic Ac | 2000 |
Activation of JNK, p38 and ERK mitogen-activated protein kinases by chromium(VI) is mediated through oxidative stress but does not affect cytotoxicity.
Topics: Adenocarcinoma; Amitrole; Catalase; Cell Division; Chelating Agents; Chromates; Drug Interactions; E | 2000 |
Expression of cyclooxygenase 2 by prostaglandin E(2) in human endometrial adenocarcinoma cell line HEC-1B.
Topics: Adenocarcinoma; Cyclooxygenase 2; Dinoprostone; Endometrial Neoplasms; Enzyme Activation; Enzyme Inh | 2000 |
PKC, p42/p44 MAPK, and p38 MAPK are required for HGF-induced proliferation of H441 cells.
Topics: Adenocarcinoma; Cell Division; Cell Membrane; Cytosol; Enzyme Inhibitors; Flavonoids; Hepatocyte Gro | 2000 |
Interleukin-1beta induces cyclo-oxygenase-2 expression in gastric cancer cells by the p38 and p44/42 mitogen-activated protein kinase signaling pathways.
Topics: Adenocarcinoma; Blotting, Western; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Flavonoids; Ge | 2001 |
TNF-alpha and interleukin 1 activate gastrin gene expression via MAPK- and PKC-dependent mechanisms.
Topics: Adenocarcinoma; Animals; Cells, Cultured; Dogs; Enzyme Inhibitors; Flavonoids; Gastrins; Gene Expres | 2001 |
Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells.
Topics: Adenocarcinoma; Apoptosis; Autocrine Communication; Cell Cycle; Chromones; Colonic Neoplasms; Cultur | 2002 |
Formation of an hER alpha-COUP-TFI complex enhances hER alpha AF-1 through Ser118 phosphorylation by MAPK.
Topics: Adenocarcinoma; Breast Neoplasms; COUP Transcription Factor I; DNA; DNA-Binding Proteins; Enzyme Inh | 2002 |