pd 98059 has been researched along with Acute Lymphoid Leukemia in 5 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, QY | 1 |
| Wei, XD | 1 |
| Chen, L | 1 |
| Yin, QS | 1 |
| Juarez, JG | 1 |
| Thien, M | 1 |
| Dela Pena, A | 1 |
| Baraz, R | 1 |
| Bradstock, KF | 1 |
| Bendall, LJ | 1 |
| Rambal, AA | 1 |
| Panaguiton, ZL | 1 |
| Kramer, L | 1 |
| Grant, S | 1 |
| Harada, H | 1 |
| Barata, JT | 1 |
| Silva, A | 1 |
| Brandao, JG | 1 |
| Nadler, LM | 1 |
| Cardoso, AA | 1 |
| Boussiotis, VA | 1 |
| Wall, NR | 1 |
| Mohammad, RM | 1 |
| Al-Katib, AM | 1 |
5 other studies available for pd 98059 and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
[Inhibitory effect of PD98059 on MAPK signaling pathway in acute lymphocytic leukemia cells].
Topics: Flavonoids; Humans; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Precursor Cell Lymphobla | 2013 |
CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK.
Topics: Animals; B-Lymphocytes; Benzylamines; Bone Marrow; Cell Line, Tumor; Chemokine CXCL12; Chemotaxis, L | 2009 |
MEK inhibitors potentiate dexamethasone lethality in acute lymphoblastic leukemia cells through the pro-apoptotic molecule BIM.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associat | 2009 |
Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells.
Topics: Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Antigens, Differentiation, T-Lymphocyte; Cell | 2004 |
Mitogen-activated protein kinase is required for bryostatin 1-induced differentiation of the human acute lymphoblastic leukemia cell line Reh.
Topics: Bacterial Proteins; Binding Sites; Blotting, Western; Bryostatins; Cell Differentiation; Enzyme Acti | 2001 |