pd 98059 has been researched along with Acute Brain Injuries in 4 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dexmedetomidine showed a protective effect on traumatically injured hippocampal cells with a maximum effect at a dosage of 1 μM." | 1.38 | Dexmedetomidine is neuroprotective in an in vitro model for traumatic brain injury. ( Coburn, M; Eberhardt, G; Fahlenkamp, AV; Loetscher, PD; Rex, S; Rossaint, R; Schoeler, M; Weis, J, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhuo, X | 1 |
| Xie, L | 1 |
| Shi, FR | 1 |
| Li, N | 1 |
| Chen, X | 1 |
| Chen, M | 1 |
| Franke, H | 1 |
| Sauer, C | 1 |
| Rudolph, C | 1 |
| Krügel, U | 1 |
| Hengstler, JG | 1 |
| Illes, P | 1 |
| Schoeler, M | 1 |
| Loetscher, PD | 1 |
| Rossaint, R | 1 |
| Fahlenkamp, AV | 1 |
| Eberhardt, G | 1 |
| Rex, S | 1 |
| Weis, J | 1 |
| Coburn, M | 1 |
| Mori, T | 1 |
| Wang, X | 1 |
| Jung, JC | 1 |
| Sumii, T | 1 |
| Singhal, AB | 1 |
| Fini, ME | 1 |
| Dixon, CE | 1 |
| Alessandrini, A | 1 |
| Lo, EH | 1 |
4 other studies available for pd 98059 and Acute Brain Injuries
| Article | Year |
|---|---|
The benefits of respective and combined use of green tea polyphenols and ERK inhibitor on the survival and neurologic outcomes in cardiac arrest rats induced by ventricular fibrillation.
Topics: Animals; Brain Injuries; Cardiopulmonary Resuscitation; Disease Models, Animal; Female; Flavonoids; | 2016 |
P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo.
Topics: Adenosine Diphosphate; Androstadienes; Animals; Apoptosis; Astrocytes; Brain Injuries; Disease Model | 2009 |
Dexmedetomidine is neuroprotective in an in vitro model for traumatic brain injury.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Injuries; Cell Count; Dexmedetomidine; Diseas | 2012 |
Mitogen-activated protein kinase inhibition in traumatic brain injury: in vitro and in vivo effects.
Topics: Animals; Brain; Brain Injuries; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Imida | 2002 |