pd 173074 has been researched along with Squamous Cell Carcinoma of Head and Neck in 4 studies
Squamous Cell Carcinoma of Head and Neck: The most common type of head and neck carcinoma that originates from cells on the surface of the NASAL CAVITY; MOUTH; PARANASAL SINUSES, SALIVARY GLANDS, and LARYNX. Mutations in TNFRSF10B, PTEN, and ING1 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) has been a longstanding challenge for head and neck oncologists, and current treatments still have limited efficacy." | 1.48 | Fibroblast growth factor receptor 3-mediated reactivation of ERK signaling promotes head and neck squamous cancer cell insensitivity to MEK inhibition. ( An, S; Ban, MJ; Byeon, HK; Kee, H; Kim, DH; Kim, JH; Kim, JW; Koh, YW; Yang, J; Yang, YJ, 2018) |
| "Head and neck squamous cell carcinoma (HNSCC) is a complex disease process involving interactions with carcinoma-associated fibroblasts and endothelial cells." | 1.38 | Inhibition of fibroblasts reduced head and neck cancer growth by targeting fibroblast growth factor receptor. ( Hart, J; Hartman, YE; Lancaster, W; Liu, Z; Rosenthal, EL; Sweeny, L, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ban, MJ | 1 |
| Byeon, HK | 1 |
| Yang, YJ | 1 |
| An, S | 1 |
| Kim, JW | 1 |
| Kim, JH | 1 |
| Kim, DH | 1 |
| Yang, J | 1 |
| Kee, H | 1 |
| Koh, YW | 1 |
| Nguyen, PT | 1 |
| Tsunematsu, T | 1 |
| Yanagisawa, S | 1 |
| Kudo, Y | 1 |
| Miyauchi, M | 1 |
| Kamata, N | 1 |
| Takata, T | 1 |
| Gyanchandani, R | 1 |
| Ortega Alves, MV | 1 |
| Myers, JN | 1 |
| Kim, S | 1 |
| Sweeny, L | 1 |
| Liu, Z | 1 |
| Lancaster, W | 1 |
| Hart, J | 1 |
| Hartman, YE | 1 |
| Rosenthal, EL | 1 |
4 other studies available for pd 173074 and Squamous Cell Carcinoma of Head and Neck
| Article | Year |
|---|---|
Fibroblast growth factor receptor 3-mediated reactivation of ERK signaling promotes head and neck squamous cancer cell insensitivity to MEK inhibition.
Topics: Animals; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neopl | 2018 |
The FGFR1 inhibitor PD173074 induces mesenchymal-epithelial transition through the transcription factor AP-1.
Topics: Carcinoma, Squamous Cell; Cell Growth Processes; Cell Line, Tumor; Cell Nucleus; Epithelial-Mesenchy | 2013 |
A proangiogenic signature is revealed in FGF-mediated bevacizumab-resistant head and neck squamous cell carcinoma.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Bevacizumab; Carcinoma, Squamou | 2013 |
Inhibition of fibroblasts reduced head and neck cancer growth by targeting fibroblast growth factor receptor.
Topics: Animals; Carcinoma, Squamous Cell; Cell Proliferation; Fibroblasts; Head and Neck Neoplasms; Humans; | 2012 |