pd 173074 has been researched along with Neoplasms in 7 studies
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Genetically defined cancer subsets, irrespective of tissue type, predict response to kinase inhibitors, and provide an important preclinical model to guide early clinical applications of novel targeted inhibitors." | 1.34 | Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling. ( Archibald, H; Dowell, L; Drew, L; Erlander, MG; Gray, NS; Greninger, P; Haber, DA; Hanke, JH; Iafrate, AJ; Lamb, J; Lee, D; Ma, XJ; Maheswaran, S; McDermott, U; Montagut, C; Njauw, CN; Raudales, R; Rothenberg, SM; Settleman, J; Sharma, SV; Sordella, R; Supko, JG; Tam, A; Tsao, H; Ulkus, LE, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| McDermott, U | 1 |
| Sharma, SV | 1 |
| Dowell, L | 1 |
| Greninger, P | 1 |
| Montagut, C | 1 |
| Lamb, J | 1 |
| Archibald, H | 1 |
| Raudales, R | 1 |
| Tam, A | 1 |
| Lee, D | 1 |
| Rothenberg, SM | 1 |
| Supko, JG | 1 |
| Sordella, R | 1 |
| Ulkus, LE | 1 |
| Iafrate, AJ | 1 |
| Maheswaran, S | 1 |
| Njauw, CN | 1 |
| Tsao, H | 1 |
| Drew, L | 1 |
| Hanke, JH | 1 |
| Ma, XJ | 1 |
| Erlander, MG | 1 |
| Gray, NS | 1 |
| Haber, DA | 1 |
| Settleman, J | 1 |
| Ahmed, SM | 1 |
| Ragunathan, P | 1 |
| Shin, J | 1 |
| Peter, S | 1 |
| Kleissle, S | 1 |
| Neuenschwander, M | 1 |
| Schäfer, R | 1 |
| Kries, JPV | 1 |
| Grüber, G | 1 |
| Dröge, P | 1 |
| Patel, A | 1 |
| Tiwari, AK | 1 |
| Chufan, EE | 1 |
| Sodani, K | 1 |
| Anreddy, N | 1 |
| Singh, S | 1 |
| Ambudkar, SV | 1 |
| Stephani, R | 1 |
| Chen, ZS | 1 |
| Herrera-Abreu, MT | 1 |
| Pearson, A | 1 |
| Campbell, J | 1 |
| Shnyder, SD | 1 |
| Knowles, MA | 1 |
| Ashworth, A | 1 |
| Turner, NC | 1 |
| Oneyama, C | 1 |
| Ikeda, J | 1 |
| Okuzaki, D | 1 |
| Suzuki, K | 1 |
| Kanou, T | 1 |
| Shintani, Y | 1 |
| Morii, E | 1 |
| Okumura, M | 1 |
| Aozasa, K | 1 |
| Okada, M | 1 |
| Chell, V | 1 |
| Balmanno, K | 1 |
| Little, AS | 1 |
| Wilson, M | 1 |
| Andrews, S | 1 |
| Blockley, L | 1 |
| Hampson, M | 1 |
| Gavine, PR | 1 |
| Cook, SJ | 1 |
| Kumar, SB | 1 |
| Narasu, L | 1 |
| Gundla, R | 1 |
| Dayam, R | 1 |
| J A R P, S | 1 |
1 review available for pd 173074 and Neoplasms
| Article | Year |
|---|---|
Fibroblast growth factor receptor inhibitors.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Drug Design; Humans; Neoplasms; Neovascular | 2013 |
6 other studies available for pd 173074 and Neoplasms
| Article | Year |
|---|---|
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor | 2007 |
The FGFR inhibitor PD173074 binds to the C-terminus of oncofetal HMGA2 and modulates its DNA-binding and transcriptional activation functions.
Topics: Adult; Chromatin; DNA; HMGA2 Protein; Humans; Neoplasms; Receptors, Fibroblast Growth Factor; Transc | 2023 |
PD173074, a selective FGFR inhibitor, reverses ABCB1-mediated drug resistance in cancer cells.
Topics: Adenosine Triphosphate; Affinity Labels; Allosteric Regulation; Antineoplastic Agents; ATP Binding C | 2013 |
Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer.
Topics: Animals; Cell Line, Tumor; Dasatinib; ErbB Receptors; Gefitinib; Heterografts; High-Throughput Scree | 2013 |
MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways.
Topics: Animals; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cluster An | 2011 |
Tumour cell responses to new fibroblast growth factor receptor tyrosine kinase inhibitors and identification of a gatekeeper mutation in FGFR3 as a mechanism of acquired resistance.
Topics: Antineoplastic Agents; Benzamides; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fe | 2013 |