pd 173074 has been researched along with Disease Models, Animal in 11 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Folic acid-induced acute kidney injury increased calvaria FGF23 mRNA and serum FGF23 and parathyroid hormone (PTH) levels at 6 h." | 3.83 | The fibroblast growth factor receptor mediates the increased FGF23 expression in acute and chronic uremia. ( Durlacher, K; Hassan, A; Levi, R; Naveh-Many, T; Silver, J, 2016) |
| "Crouzon syndrome is caused by mutations in fibroblast growth factor receptor 2 (FGFR2) leading to constitutive activation of receptors in the absence of ligand binding." | 1.33 | A model for the pharmacological treatment of crouzon syndrome. ( Darvann, T; Morriss-Kay, G; Ornitz, DM; Perlyn, CA; Tenenbaum, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Takasugi, S | 1 |
| Shioyama, M | 1 |
| Kitade, M | 1 |
| Nagata, M | 1 |
| Yamaji, T | 1 |
| Martin, L | 1 |
| Kaci, N | 1 |
| Estibals, V | 1 |
| Goudin, N | 1 |
| Garfa-Traore, M | 1 |
| Benoist-Lasselin, C | 1 |
| Dambroise, E | 1 |
| Legeai-Mallet, L | 1 |
| Czaya, B | 1 |
| Seeherunvong, W | 1 |
| Singh, S | 1 |
| Yanucil, C | 1 |
| Ruiz, P | 1 |
| Quiroz, Y | 1 |
| Grabner, A | 2 |
| Katsoufis, C | 1 |
| Swaminathan, S | 1 |
| Abitbol, C | 1 |
| Rodriguez-Iturbe, B | 1 |
| Faul, C | 2 |
| Freundlich, M | 1 |
| Di Marco, GS | 1 |
| Reuter, S | 1 |
| Kentrup, D | 1 |
| Amaral, AP | 1 |
| Fobker, M | 1 |
| Stypmann, J | 1 |
| Pavenstädt, H | 1 |
| Wolf, M | 1 |
| Brand, M | 1 |
| Bai, YP | 1 |
| Shang, K | 1 |
| Chen, H | 1 |
| Ding, F | 1 |
| Wang, Z | 1 |
| Liang, C | 1 |
| Xu, Y | 1 |
| Sun, MH | 1 |
| Li, YY | 1 |
| Hassan, A | 1 |
| Durlacher, K | 1 |
| Silver, J | 1 |
| Naveh-Many, T | 1 |
| Levi, R | 1 |
| Zheng, Y | 1 |
| Ma, H | 1 |
| Hu, E | 1 |
| Huang, Z | 1 |
| Cheng, X | 1 |
| Xiong, C | 1 |
| Li, J | 1 |
| Ye, Y | 1 |
| Wang, M | 1 |
| Lu, L | 1 |
| Han, C | 1 |
| Zhou, Y | 1 |
| Zhang, J | 1 |
| Yu, Z | 1 |
| Zhang, X | 1 |
| Zhao, C | 1 |
| Wen, J | 1 |
| Kan, Q | 1 |
| Wu, Q | 1 |
| Bhole, A | 1 |
| Qin, H | 1 |
| Karp, J | 1 |
| Malek, S | 1 |
| Cowell, JK | 1 |
| Ren, M | 1 |
| Perlyn, CA | 1 |
| Morriss-Kay, G | 1 |
| Darvann, T | 1 |
| Tenenbaum, M | 1 |
| Ornitz, DM | 1 |
11 other studies available for pd 173074 and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Involvement of estrogen in phosphorus-induced nephrocalcinosis through fibroblast growth factor 23.
Topics: Animals; Aorta; Bone Density; Calcium; Disease Models, Animal; Estrogens; Female; Fibroblast Growth | 2020 |
Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
Topics: Achondroplasia; Animals; Bone Development; Carrier Proteins; Cartilage; Cell Differentiation; Cell L | 2018 |
Cardioprotective Effects of Paricalcitol Alone and in Combination With FGF23 Receptor Inhibition in Chronic Renal Failure: Experimental and Clinical Studies.
Topics: Adolescent; Animals; Cardio-Renal Syndrome; Cardiomyopathies; Child; Disease Models, Animal; Drug Th | 2019 |
Treatment of established left ventricular hypertrophy with fibroblast growth factor receptor blockade in an animal model of CKD.
Topics: Animals; Disease Models, Animal; Echocardiography; Heart Ventricles; Hypertrophy, Left Ventricular; | 2014 |
FGF-1/-3/FGFR4 signaling in cancer-associated fibroblasts promotes tumor progression in colon cancer through Erk and MMP-7.
Topics: Animals; Azoxymethane; Cell Line, Tumor; Colitis, Ulcerative; Colonic Neoplasms; Dextran Sulfate; Di | 2015 |
The fibroblast growth factor receptor mediates the increased FGF23 expression in acute and chronic uremia.
Topics: Acute Kidney Injury; Adenine; Animals; Chronic Disease; Disease Models, Animal; Fibroblast Growth Fa | 2016 |
Inhibition of FGFR Signaling With PD173074 Ameliorates Monocrotaline-induced Pulmonary Arterial Hypertension and Rescues BMPR-II Expression.
Topics: Adolescent; Adult; Animals; Apoptosis; Arterioles; Bone Morphogenetic Protein Receptors, Type II; Ce | 2015 |
The over-expression of FGFR4 could influence the features of gastric cancer cells and inhibit the efficacy of PD173074 and 5-fluorouracil towards gastric cancer.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Flu | 2016 |
SCLLTargeting FGFR1 to suppress leukemogenesis in syndromic and de novo AML in murine models.
Topics: Animals; Benzamides; Benzimidazoles; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Proliferatio | 2016 |
A model for the pharmacological treatment of crouzon syndrome.
Topics: Animals; Cranial Sutures; Craniofacial Dysostosis; Cysteine; Disease Models, Animal; Mice; Mice, Mut | 2006 |