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pd 173074 and Cell Transformation, Neoplastic

pd 173074 has been researched along with Cell Transformation, Neoplastic in 4 studies

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
"Inhibition of FGFR kinase corrects the aneuploidy, and oral administration of an FGFR inhibitor prolongs survival of mice harboring intracranial FGFR3-TACC3-initiated glioma."1.38Transforming fusions of FGFR and TACC genes in human glioblastoma. ( Aldape, K; Brat, DJ; Castano, A; Ceccarelli, M; Chan, JM; Finocchiaro, G; Gao, Z; Golfinos, JG; Guha, A; Iavarone, A; Lasorella, A; Liu, EM; Mikkelsen, T; Niola, F; Pellegatta, S; Porrati, P; Qiu, K; Rabadan, R; Reichel, J; Riccardi, R; Singh, D; Sullivan, R; Zagzag, D; Zoppoli, P, 2012)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oneyama, C1
Ikeda, J1
Okuzaki, D1
Suzuki, K1
Kanou, T1
Shintani, Y1
Morii, E1
Okumura, M1
Aozasa, K1
Okada, M1
Crose, LE1
Etheridge, KT1
Chen, C1
Belyea, B1
Talbot, LJ1
Bentley, RC1
Linardic, CM1
Singh, D1
Chan, JM1
Zoppoli, P1
Niola, F1
Sullivan, R1
Castano, A1
Liu, EM1
Reichel, J1
Porrati, P1
Pellegatta, S1
Qiu, K1
Gao, Z1
Ceccarelli, M1
Riccardi, R1
Brat, DJ1
Guha, A1
Aldape, K1
Golfinos, JG1
Zagzag, D1
Mikkelsen, T1
Finocchiaro, G1
Lasorella, A1
Rabadan, R1
Iavarone, A1
Yang, ZQ1
Moffa, AB1
Haddad, R1
Streicher, KL1
Ethier, SP1

Other Studies

4 other studies available for pd 173074 and Cell Transformation, Neoplastic

ArticleYear
MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways.
    Oncogene, 2011, Aug-11, Volume: 30, Issue:32

    Topics: Animals; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cluster An

2011
FGFR4 blockade exerts distinct antitumorigenic effects in human embryonal versus alveolar rhabdomyosarcoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Jul-15, Volume: 18, Issue:14

    Topics: Animals; bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Gene

2012
Transforming fusions of FGFR and TACC genes in human glioblastoma.
    Science (New York, N.Y.), 2012, Sep-07, Volume: 337, Issue:6099

    Topics: Aneuploidy; Animals; Antineoplastic Agents; Benzamides; Brain Neoplasms; Cell Transformation, Neopla

2012
Transforming properties of TC-1 in human breast cancer: interaction with FGFR2 and beta-catenin signaling pathways.
    International journal of cancer, 2007, Sep-15, Volume: 121, Issue:6

    Topics: Animals; beta Catenin; Blotting, Northern; Breast Neoplasms; Cell Line, Tumor; Cell Transformation,

2007