pd 173074 has been researched along with Breast Neoplasms in 9 studies
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pools of S115 mouse breast cancer cells expressing shRNA against FGFR1, 2 and 3 were created by lentiviral gene transfer, resulting in cells with downregulated expression of FGFR1, FGFR2 or FGFR3 (shR1, shR2 and shR3 cells, respectively) and shLacZ controls." | 1.38 | Differential roles of fibroblast growth factor receptors (FGFR) 1, 2 and 3 in the regulation of S115 breast cancer cell growth. ( Dey, JH; Härkönen, PL; Heikkilä, JE; Hynes, NE; Kähkönen, TE; Liu, Q; Nilsson, EM; Tarkkonen, KM; Tuomela, JM, 2012) |
| "Basal-like breast cancer cell lines were found to express FGF2 ligand (11/21 positive) and, similarly, 62% of basal-like breast cancers expressed FGF2, as assessed by immunohistochemistry compared with 5% of nonbasal breast cancers (P < 0." | 1.37 | FGFR signaling promotes the growth of triple-negative and basal-like breast cancer cell lines both in vitro and in vivo. ( Ashworth, A; Herrera-Abreu, MT; Johnson, D; Mackay, A; Natrajan, R; Pearson, A; Reis-Filho, JS; Reynolds, AR; Sharpe, R; Turner, NC; Welti, JC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qian, X | 1 |
| Anzovino, A | 1 |
| Kim, S | 1 |
| Suyama, K | 1 |
| Yao, J | 1 |
| Hulit, J | 1 |
| Agiostratidou, G | 1 |
| Chandiramani, N | 1 |
| McDaid, HM | 1 |
| Nagi, C | 1 |
| Cohen, HW | 1 |
| Phillips, GR | 1 |
| Norton, L | 1 |
| Hazan, RB | 1 |
| Ye, T | 1 |
| Wei, X | 1 |
| Yin, T | 1 |
| Xia, Y | 1 |
| Li, D | 1 |
| Shao, B | 1 |
| Song, X | 1 |
| He, S | 1 |
| Luo, M | 1 |
| Gao, X | 1 |
| He, Z | 1 |
| Luo, C | 1 |
| Xiong, Y | 1 |
| Wang, N | 1 |
| Zeng, J | 1 |
| Zhao, L | 1 |
| Shen, G | 1 |
| Xie, Y | 1 |
| Yu, L | 1 |
| Wei, Y | 1 |
| Tarkkonen, K | 1 |
| Ruohola, J | 1 |
| Härkönen, P | 1 |
| Sharpe, R | 1 |
| Pearson, A | 1 |
| Herrera-Abreu, MT | 1 |
| Johnson, D | 1 |
| Mackay, A | 1 |
| Welti, JC | 1 |
| Natrajan, R | 1 |
| Reynolds, AR | 1 |
| Reis-Filho, JS | 1 |
| Ashworth, A | 1 |
| Turner, NC | 1 |
| Chell, V | 1 |
| Balmanno, K | 1 |
| Little, AS | 1 |
| Wilson, M | 1 |
| Andrews, S | 1 |
| Blockley, L | 1 |
| Hampson, M | 1 |
| Gavine, PR | 1 |
| Cook, SJ | 1 |
| Tarkkonen, KM | 1 |
| Nilsson, EM | 1 |
| Kähkönen, TE | 1 |
| Dey, JH | 1 |
| Heikkilä, JE | 1 |
| Tuomela, JM | 1 |
| Liu, Q | 1 |
| Hynes, NE | 2 |
| Härkönen, PL | 1 |
| Koziczak, M | 1 |
| Holbro, T | 1 |
| Pal, M | 1 |
| Moffa, A | 1 |
| Sreekumar, A | 1 |
| Ethier, SP | 2 |
| Barder, TJ | 1 |
| Chinnaiyan, A | 1 |
| Lubman, DM | 1 |
| Yang, ZQ | 1 |
| Moffa, AB | 1 |
| Haddad, R | 1 |
| Streicher, KL | 1 |
9 other studies available for pd 173074 and Breast Neoplasms
| Article | Year |
|---|---|
N-cadherin/FGFR promotes metastasis through epithelial-to-mesenchymal transition and stem/progenitor cell-like properties.
Topics: Aldehyde Dehydrogenase; Animals; Benzamides; Breast Neoplasms; Cadherins; Cell Movement; Cell Prolif | 2014 |
Inhibition of FGFR signaling by PD173074 improves antitumor immunity and impairs breast cancer metastasis.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; F | 2014 |
Fibroblast growth factor 8 induced downregulation of thrombospondin 1 is mediated by the MEK/ERK and PI3K pathways in breast cancer cells.
Topics: Angiogenesis Modulating Agents; Animals; Blotting, Western; Breast Neoplasms; Butadienes; Cell Line; | 2010 |
FGFR signaling promotes the growth of triple-negative and basal-like breast cancer cell lines both in vitro and in vivo.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mammary Neoplasms, | 2011 |
Tumour cell responses to new fibroblast growth factor receptor tyrosine kinase inhibitors and identification of a gatekeeper mutation in FGFR3 as a mechanism of acquired resistance.
Topics: Antineoplastic Agents; Benzamides; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Fe | 2013 |
Differential roles of fibroblast growth factor receptors (FGFR) 1, 2 and 3 in the regulation of S115 breast cancer cell growth.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Fibroblast Growth Factor 8; | 2012 |
Blocking of FGFR signaling inhibits breast cancer cell proliferation through downregulation of D-type cyclins.
Topics: Breast Neoplasms; Cell Division; Cyclin D; Cyclins; Down-Regulation; Female; G1 Phase; Humans; In Vi | 2004 |
Differential phosphoprotein mapping in cancer cells using protein microarrays produced from 2-D liquid fractionation.
Topics: Breast Neoplasms; Cell Line, Tumor; Chemical Fractionation; Chromatography, High Pressure Liquid; Hu | 2006 |
Transforming properties of TC-1 in human breast cancer: interaction with FGFR2 and beta-catenin signaling pathways.
Topics: Animals; beta Catenin; Blotting, Northern; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, | 2007 |