pd 173074 has been researched along with Achondroplasia in 2 studies
Achondroplasia: An autosomal dominant disorder that is the most frequent form of short-limb dwarfism. Affected individuals exhibit short stature caused by rhizomelic shortening of the limbs, characteristic facies with frontal bossing and mid-face hypoplasia, exaggerated lumbar lordosis, limitation of elbow extension, GENU VARUM, and trident hand. (Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim, MIM#100800, April 20, 2001)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martin, L | 1 |
| Kaci, N | 1 |
| Estibals, V | 1 |
| Goudin, N | 1 |
| Garfa-Traore, M | 1 |
| Benoist-Lasselin, C | 1 |
| Dambroise, E | 1 |
| Legeai-Mallet, L | 1 |
| Gudernova, I | 1 |
| Vesela, I | 1 |
| Balek, L | 1 |
| Buchtova, M | 1 |
| Dosedelova, H | 1 |
| Kunova, M | 1 |
| Pivnicka, J | 1 |
| Jelinkova, I | 1 |
| Roubalova, L | 1 |
| Kozubik, A | 1 |
| Krejci, P | 1 |
2 other studies available for pd 173074 and Achondroplasia
| Article | Year |
|---|---|
Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
Topics: Achondroplasia; Animals; Bone Development; Carrier Proteins; Cartilage; Cell Differentiation; Cell L | 2018 |
Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes.
Topics: Achondroplasia; Animals; Benzamides; Cartilage; Catalysis; Cells, Cultured; Chick Embryo; Chondrocyt | 2016 |