pd 169316 has been researched along with Retinoblastoma in 1 studies
2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole: p38 MAP kinase inhibitor
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poulaki, V | 1 |
| Mitsiades, CS | 1 |
| Joussen, AM | 1 |
| Lappas, A | 1 |
| Kirchhof, B | 1 |
| Mitsiades, N | 1 |
1 other study available for pd 169316 and Retinoblastoma
| Article | Year |
|---|---|
Constitutive nuclear factor-kappaB activity is crucial for human retinoblastoma cell viability.
Topics: Antineoplastic Agents; Apoptosis; Calpain; Caspase 3; Caspases; Cell Survival; Dipeptides; DNA; Doxo | 2002 |