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pd 169316 and Necrosis

pd 169316 has been researched along with Necrosis in 2 studies

2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole: p38 MAP kinase inhibitor

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Calyculin A neurotoxicity was partially sensitive to 100 microM z-VAD-fmk."5.31Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neurons. ( Gwag, BJ; Han, KS; Jung, YK; Kim, EY; Kim, SU; Ko, HW; Ryu, BR; Yoon, WJ, 2000)
"Calyculin A neurotoxicity was partially sensitive to 100 microM z-VAD-fmk."1.31Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neurons. ( Gwag, BJ; Han, KS; Jung, YK; Kim, EY; Kim, SU; Ko, HW; Ryu, BR; Yoon, WJ, 2000)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schwertz, H1
Carter, JM1
Abdudureheman, M1
Russ, M1
Buerke, U1
Schlitt, A1
Müller-Werdan, U1
Prondzinsky, R1
Werdan, K1
Buerke, M1
Ko, HW1
Han, KS1
Kim, EY1
Ryu, BR1
Yoon, WJ1
Jung, YK1
Kim, SU1
Gwag, BJ1

Other Studies

2 other studies available for pd 169316 and Necrosis

ArticleYear
Myocardial ischemia/reperfusion causes VDAC phosphorylation which is reduced by cardioprotection with a p38 MAP kinase inhibitor.
    Proteomics, 2007, Volume: 7, Issue:24

    Topics: Animals; Antibodies, Phospho-Specific; Cardiotonic Agents; Electrophoresis, Gel, Two-Dimensional; He

2007
Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neurons.
    Journal of neurochemistry, 2000, Volume: 74, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cerebral

2000