pd 169316 has been researched along with Necrosis in 2 studies
2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole: p38 MAP kinase inhibitor
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Calyculin A neurotoxicity was partially sensitive to 100 microM z-VAD-fmk." | 5.31 | Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neurons. ( Gwag, BJ; Han, KS; Jung, YK; Kim, EY; Kim, SU; Ko, HW; Ryu, BR; Yoon, WJ, 2000) |
| "Calyculin A neurotoxicity was partially sensitive to 100 microM z-VAD-fmk." | 1.31 | Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neurons. ( Gwag, BJ; Han, KS; Jung, YK; Kim, EY; Kim, SU; Ko, HW; Ryu, BR; Yoon, WJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schwertz, H | 1 |
| Carter, JM | 1 |
| Abdudureheman, M | 1 |
| Russ, M | 1 |
| Buerke, U | 1 |
| Schlitt, A | 1 |
| Müller-Werdan, U | 1 |
| Prondzinsky, R | 1 |
| Werdan, K | 1 |
| Buerke, M | 1 |
| Ko, HW | 1 |
| Han, KS | 1 |
| Kim, EY | 1 |
| Ryu, BR | 1 |
| Yoon, WJ | 1 |
| Jung, YK | 1 |
| Kim, SU | 1 |
| Gwag, BJ | 1 |
2 other studies available for pd 169316 and Necrosis
| Article | Year |
|---|---|
Myocardial ischemia/reperfusion causes VDAC phosphorylation which is reduced by cardioprotection with a p38 MAP kinase inhibitor.
Topics: Animals; Antibodies, Phospho-Specific; Cardiotonic Agents; Electrophoresis, Gel, Two-Dimensional; He | 2007 |
Synergetic activation of p38 mitogen-activated protein kinase and caspase-3-like proteases for execution of calyculin A-induced apoptosis but not N-methyl-d-aspartate-induced necrosis in mouse cortical neurons.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cerebral | 2000 |