pd 153035 has been researched along with Invasiveness, Neoplasm in 5 studies
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline: structure given in first source
PD-153035 : A member of the class of quinazolines carrying a 3-bromophenylamino substituent at position 4 and two methoxy substituents at positions 6 and 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant pleural mesothelioma is notoriously refractory to aggressive multimodality therapy." | 1.33 | The selective epidermal growth factor receptor tyrosine kinase inhibitor PD153035 suppresses expression of prometastasis phenotypes in malignant pleural mesothelioma cells in vitro. ( Alleva, AM; Cole, GW; Maxhimer, JB; Nguyen, DM; Reddy, RM; Schrump, DS; Zuo, J, 2005) |
| "Because the prostate and breast cancer lines usually present autocrine stimulatory loops involving EGFR, we also examined transgenic adenocarcinoma mouse prostate C1 and MDA-468 treated with the EGFR-specific kinase inhibitor PD153035 to determine whether invasiveness is dependent on EGFR signaling." | 1.30 | A role for phospholipase C-gamma-mediated signaling in tumor cell invasion. ( Greenberg, NM; Kassis, J; Kim, HG; Lo, H; Moellinger, J; Wells, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kassis, J | 2 |
| Maeda, A | 1 |
| Teramoto, N | 1 |
| Takada, K | 1 |
| Wu, C | 1 |
| Klein, G | 1 |
| Wells, A | 2 |
| Cole, GW | 1 |
| Alleva, AM | 1 |
| Reddy, RM | 1 |
| Maxhimer, JB | 1 |
| Zuo, J | 1 |
| Schrump, DS | 1 |
| Nguyen, DM | 1 |
| Kondapaka, SB | 1 |
| Fridman, R | 1 |
| Reddy, KB | 1 |
| Moellinger, J | 1 |
| Lo, H | 1 |
| Greenberg, NM | 1 |
| Kim, HG | 1 |
| Bergmann-Leitner, ES | 1 |
| Bennett, TA | 1 |
| Hacker, NF | 1 |
| Stromberg, K | 1 |
| Stetler-Stevenson, WG | 1 |
5 other studies available for pd 153035 and Invasiveness, Neoplasm
| Article | Year |
|---|---|
EBV-expressing AGS gastric carcinoma cell sublines present increased motility and invasiveness.
Topics: Carcinoma, Signet Ring Cell; Cell Movement; Collagen; Drug Combinations; Enzyme Inhibitors; ErbB Rec | 2002 |
The selective epidermal growth factor receptor tyrosine kinase inhibitor PD153035 suppresses expression of prometastasis phenotypes in malignant pleural mesothelioma cells in vitro.
Topics: Antineoplastic Agents; Cell Movement; Cell Proliferation; Cocarcinogenesis; Collagen; Dose-Response | 2005 |
Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells.
Topics: Amphiregulin; Antineoplastic Agents; Breast Neoplasms; Cell Division; Collagenases; EGF Family of Pr | 1997 |
A role for phospholipase C-gamma-mediated signaling in tumor cell invasion.
Topics: Adenocarcinoma; Animals; Autocrine Communication; Breast Neoplasms; Cell Line; Diffusion Chambers, C | 1999 |
Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells.
Topics: Antigens, CD; Autocrine Communication; Carcinoma; Cell Adhesion; Cell Movement; Cell Size; DNA, Anti | 2001 |