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pd 153035 and Glomerulosclerosis, Focal Segmental

pd 153035 has been researched along with Glomerulosclerosis, Focal Segmental in 1 studies

4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline: structure given in first source
PD-153035 : A member of the class of quinazolines carrying a 3-bromophenylamino substituent at position 4 and two methoxy substituents at positions 6 and 7.

Glomerulosclerosis, Focal Segmental: A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.

Research Excerpts

ExcerptRelevanceReference
"Hypertension is frequently associated with the development of renal vascular and glomerular fibrosis."1.32Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition. ( Chansel, D; Chatziantoniou, C; Dussaule, JC; Flamant, M; François, H; Placier, S; Tharaux, PL, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
François, H1
Placier, S1
Flamant, M1
Tharaux, PL1
Chansel, D1
Dussaule, JC1
Chatziantoniou, C1

Other Studies

1 other study available for pd 153035 and Glomerulosclerosis, Focal Segmental

ArticleYear
Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:7

    Topics: Animals; Capillaries; Collagen; Collagen Type I; Creatinine; Endothelin-1; ErbB Receptors; Fibrosis;

2004