pd 153035 and Glioma
pd 153035 has been researched along with Glioma in 5 studies
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline: structure given in first source
PD-153035 : A member of the class of quinazolines carrying a 3-bromophenylamino substituent at position 4 and two methoxy substituents at positions 6 and 7.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Sun, J | 1 |
| Cai, L | 1 |
| Zhang, K | 1 |
| Zhang, A | 1 |
| Pu, P | 1 |
| Yang, W | 1 |
| Gao, S | 1 |
| Hartel, I | 1 |
| Ronellenfitsch, M | 1 |
| Wanka, C | 1 |
| Wolking, S | 1 |
| Steinbach, JP | 2 |
| Rieger, J | 1 |
| Wang, H | 1 |
| Yu, JM | 1 |
| Song, XR | 1 |
| Yang, GR | 1 |
| Mu, DB | 1 |
| Zhao, SQ | 1 |
| Wang, XW | 1 |
| Wei, L | 1 |
| Liu, YL | 1 |
| Song, B | 1 |
| Fu, Z | 1 |
| Teng, XP | 1 |
| Li, B | 1 |
| Chang, CM | 1 |
| Yuan, M | 1 |
| McKenna, WG | 1 |
| Shu, HK | 1 |
| Eisenmann, C | 1 |
| Klumpp, A | 1 |
| Weller, M | 1 |
Trials
1 trial available for pd 153035 and Glioma
| Article | Year |
|---|---|
A pilot study on EGFR-targeted molecular imaging of PET/CT With 11C-PD153035 in human gliomas.
Topics: Adult; Aged; Biological Transport; Carbon Radioisotopes; ErbB Receptors; Female; Gene Expression Reg | 2014 |
Other Studies
4 other studies available for pd 153035 and Glioma
| Article | Year |
|---|---|
Activation of AMP-activated kinase modulates sensitivity of glioma cells against epidermal growth factor receptor inhibition.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Cell Hypoxia; C | 2016 |
[Molecular imaging of epidermal growth factor receptor in glioma-bearing rats].
Topics: Animals; Brain Neoplasms; Carbon Radioisotopes; Cell Line, Tumor; ErbB Receptors; Gastrointestinal T | 2008 |
Resistance to small molecule inhibitors of epidermal growth factor receptor in malignant gliomas.
Topics: Antineoplastic Agents; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cyclin-Dependent Kinase | 2003 |
Co-inhibition of epidermal growth factor receptor and type 1 insulin-like growth factor receptor synergistically sensitizes human malignant glioma cells to CD95L-induced apoptosis.
Topics: Apoptosis; Brain Neoplasms; Caspase 8; Caspases; Cell Line, Tumor; Enzyme Inhibitors; ErbB Receptors | 2004 |