pd 153035 has been researched along with Fibrosis in 2 studies
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline: structure given in first source
PD-153035 : A member of the class of quinazolines carrying a 3-bromophenylamino substituent at position 4 and two methoxy substituents at positions 6 and 7.
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertension is frequently associated with the development of renal vascular and glomerular fibrosis." | 1.32 | Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition. ( Chansel, D; Chatziantoniou, C; Dussaule, JC; Flamant, M; François, H; Placier, S; Tharaux, PL, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Flamant, M | 2 |
| Tharaux, PL | 2 |
| Placier, S | 2 |
| Henrion, D | 1 |
| Coffman, T | 1 |
| Chatziantoniou, C | 2 |
| Dussaule, JC | 2 |
| François, H | 1 |
| Chansel, D | 1 |
2 other studies available for pd 153035 and Fibrosis
| Article | Year |
|---|---|
Epidermal growth factor receptor trans-activation mediates the tonic and fibrogenic effects of endothelin in the aortic wall of transgenic mice.
Topics: Animals; Aorta; Blood Pressure; Collagen Type I; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; | 2003 |
Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition.
Topics: Animals; Capillaries; Collagen; Collagen Type I; Creatinine; Endothelin-1; ErbB Receptors; Fibrosis; | 2004 |