pd 153035 has been researched along with Cell Transformation, Neoplastic in 4 studies
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline: structure given in first source
PD-153035 : A member of the class of quinazolines carrying a 3-bromophenylamino substituent at position 4 and two methoxy substituents at positions 6 and 7.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hepatocellular carcinoma is a major cause of cancer-related deaths." | 1.33 | Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells. ( Avila, MA; Berasain, C; Castillo, J; Erroba, E; Lee, DC; Perugorría, MJ; Prieto, J; Santamaría, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castillo, J | 1 |
| Erroba, E | 1 |
| Perugorría, MJ | 1 |
| Santamaría, M | 1 |
| Lee, DC | 1 |
| Prieto, J | 1 |
| Avila, MA | 1 |
| Berasain, C | 1 |
| Fry, DW | 1 |
| Kraker, AJ | 1 |
| McMichael, A | 1 |
| Ambroso, LA | 1 |
| Nelson, JM | 1 |
| Leopold, WR | 1 |
| Connors, RW | 1 |
| Bridges, AJ | 1 |
| Gangarosa, LM | 1 |
| Sizemore, N | 1 |
| Graves-Deal, R | 1 |
| Oldham, SM | 1 |
| Der, CJ | 1 |
| Coffey, RJ | 1 |
| Chen, N | 1 |
| Ma, WY | 1 |
| She, QB | 1 |
| Wu, E | 1 |
| Liu, G | 1 |
| Bode, AM | 1 |
| Dong, Z | 1 |
4 other studies available for pd 153035 and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Amphiregulin contributes to the transformed phenotype of human hepatocellular carcinoma cells.
Topics: Aged; Amphiregulin; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Growth Processes; Cell Line, | 2006 |
A specific inhibitor of the epidermal growth factor receptor tyrosine kinase.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Epidermal Growth Factor; ErbB Receptors; Fibrob | 1994 |
A raf-independent epidermal growth factor receptor autocrine loop is necessary for Ras transformation of rat intestinal epithelial cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Enzyme Inhibitors; ErbB Receptors; Intestinal M | 1997 |
Transactivation of the epidermal growth factor receptor is involved in 12-O-tetradecanoylphorbol-13-acetate-induced signal transduction.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Dose-Response Relations | 2001 |