pd 153035 has been researched along with Carcinoma, Non-Small Cell Lung in 6 studies
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline: structure given in first source
PD-153035 : A member of the class of quinazolines carrying a 3-bromophenylamino substituent at position 4 and two methoxy substituents at positions 6 and 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gefitinib is an EGFR-TK inhibitor that is clinically used to treat NSCLC; however, this drug frequently causes adverse effects, including skin eruptions." | 1.36 | Epidermal growth factor receptor tyrosine kinase inhibitors induce CCL2 and CCL5 via reduction in IL-1R2 in keratinocytes. ( Muro, Y; Shimoyama, Y; Sugiura, K; Tomita, Y; Yamaki, M, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, GN | 1 |
| Zhang, YK | 1 |
| Wang, YJ | 1 |
| Gupta, P | 1 |
| Ashby, CR | 1 |
| Alqahtani, S | 1 |
| Deng, T | 1 |
| Bates, SE | 1 |
| Kaddoumi, A | 1 |
| Wurpel, JND | 1 |
| Lei, YX | 1 |
| Chen, ZS | 1 |
| Dai, D | 1 |
| Li, XF | 1 |
| Wang, J | 1 |
| Liu, JJ | 1 |
| Zhu, YJ | 1 |
| Zhang, Y | 1 |
| Wang, Q | 1 |
| Xu, WG | 1 |
| Liu, N | 1 |
| Li, M | 1 |
| Li, X | 1 |
| Meng, X | 2 |
| Yang, G | 1 |
| Zhao, S | 1 |
| Yang, Y | 1 |
| Ma, L | 2 |
| Fu, Z | 1 |
| Yu, J | 2 |
| Pantaleo, MA | 1 |
| Nannini, M | 1 |
| Fanti, S | 1 |
| Boschi, S | 1 |
| Lollini, PL | 1 |
| Biasco, G | 1 |
| Yamaki, M | 1 |
| Sugiura, K | 1 |
| Muro, Y | 1 |
| Shimoyama, Y | 1 |
| Tomita, Y | 1 |
| Loo, BW | 1 |
| Murphy, JD | 1 |
| Sun, X | 1 |
6 other studies available for pd 153035 and Carcinoma, Non-Small Cell Lung
| Article | Year |
|---|---|
Epidermal growth factor receptor (EGFR) inhibitor PD153035 reverses ABCG2-mediated multidrug resistance in non-small cell lung cancer: In vitro and in vivo.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Carcinoma, Non-Small-Cell Lung; Ce | 2018 |
Predictive efficacy of (11)C-PD153035 PET imaging for EGFR-tyrosine kinase inhibitor sensitivity in non-small cell lung cancer patients.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Carbon Radioisotopes; Carcinoma, Non-Small-Cell L | 2016 |
PET-based biodistribution and radiation dosimetry of epidermal growth factor receptor-selective tracer 11C-PD153035 in humans.
Topics: Adult; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Female; Humans; Ligands | 2009 |
Molecular imaging of EGFR: it's time to go beyond receptor expression.
Topics: Adult; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Female; Humans; Ligands | 2009 |
Epidermal growth factor receptor tyrosine kinase inhibitors induce CCL2 and CCL5 via reduction in IL-1R2 in keratinocytes.
Topics: Acneiform Eruptions; Adolescent; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Case-Control | 2010 |
Molecular imaging with 11C-PD153035 PET/CT predicts survival in non-small cell lung cancer treated with EGFR-TKI: a pilot study.
Topics: Aged; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; ErbB Receptors; E | 2011 |