pd 153035 has been researched along with Cancer of Prostate in 5 studies
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline: structure given in first source
PD-153035 : A member of the class of quinazolines carrying a 3-bromophenylamino substituent at position 4 and two methoxy substituents at positions 6 and 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In vivo, the human prostate cancer xenografts in mouse war accurately visualized after i." | 1.36 | Synthesis and initial tumor affinity testing of iodine-123 labelled EGFR-affine agents as potential imaging probes for hormone-refractory prostate cancer. ( Fozing, T; Samnick, S; Scheuer, C, 2010) |
| "Because the prostate and breast cancer lines usually present autocrine stimulatory loops involving EGFR, we also examined transgenic adenocarcinoma mouse prostate C1 and MDA-468 treated with the EGFR-specific kinase inhibitor PD153035 to determine whether invasiveness is dependent on EGFR signaling." | 1.30 | A role for phospholipase C-gamma-mediated signaling in tumor cell invasion. ( Greenberg, NM; Kassis, J; Kim, HG; Lo, H; Moellinger, J; Wells, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abisoye-Ogunniyan, A | 1 |
| Lin, H | 1 |
| Ghebremedhin, A | 1 |
| Salam, AB | 1 |
| Karanam, B | 1 |
| Theodore, S | 1 |
| Jones-Trich, J | 1 |
| Davis, M | 1 |
| Grizzle, W | 1 |
| Wang, H | 1 |
| Yates, C | 1 |
| Fozing, T | 1 |
| Scheuer, C | 1 |
| Samnick, S | 1 |
| Mimeault, M | 1 |
| Pommery, N | 1 |
| Hénichart, JP | 1 |
| Bos, M | 1 |
| Mendelsohn, J | 1 |
| Kim, YM | 1 |
| Albanell, J | 1 |
| Fry, DW | 1 |
| Baselga, J | 1 |
| Kassis, J | 1 |
| Moellinger, J | 1 |
| Lo, H | 1 |
| Greenberg, NM | 1 |
| Kim, HG | 1 |
| Wells, A | 1 |
5 other studies available for pd 153035 and Cancer of Prostate
| Article | Year |
|---|---|
Transcriptional repressor Kaiso promotes epithelial to mesenchymal transition and metastasis in prostate cancer through direct regulation of miR-200c.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Epidermal Growth Factor; Epithelial- | 2018 |
Synthesis and initial tumor affinity testing of iodine-123 labelled EGFR-affine agents as potential imaging probes for hormone-refractory prostate cancer.
Topics: Animals; Antibodies, Monoclonal; Biological Transport; Cell Line, Tumor; Drug Resistance, Neoplasm; | 2010 |
Synergistic antiproliferative and apoptotic effects induced by epidermal growth factor receptor and protein kinase a inhibitors in human prostatic cancer cell lines.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Cell Division; Cell Separation; Ceramides; Cyclic AMP; C | 2003 |
PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Enzyme Inhibitors; Er | 1997 |
A role for phospholipase C-gamma-mediated signaling in tumor cell invasion.
Topics: Adenocarcinoma; Animals; Autocrine Communication; Breast Neoplasms; Cell Line; Diffusion Chambers, C | 1999 |