pd 153035 has been researched along with Adenocarcinoma in 4 studies
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline: structure given in first source
PD-153035 : A member of the class of quinazolines carrying a 3-bromophenylamino substituent at position 4 and two methoxy substituents at positions 6 and 7.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because the prostate and breast cancer lines usually present autocrine stimulatory loops involving EGFR, we also examined transgenic adenocarcinoma mouse prostate C1 and MDA-468 treated with the EGFR-specific kinase inhibitor PD153035 to determine whether invasiveness is dependent on EGFR signaling." | 1.30 | A role for phospholipase C-gamma-mediated signaling in tumor cell invasion. ( Greenberg, NM; Kassis, J; Kim, HG; Lo, H; Moellinger, J; Wells, A, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ogunwobi, OO | 1 |
| Beales, IL | 1 |
| Xiong, X | 1 |
| Fu, L | 1 |
| Wang, L | 1 |
| Cai, H | 1 |
| Li, L | 1 |
| Jiang, H | 1 |
| Duan, W | 1 |
| Mei, C | 1 |
| Bos, M | 1 |
| Mendelsohn, J | 1 |
| Kim, YM | 1 |
| Albanell, J | 1 |
| Fry, DW | 1 |
| Baselga, J | 1 |
| Kassis, J | 1 |
| Moellinger, J | 1 |
| Lo, H | 1 |
| Greenberg, NM | 1 |
| Kim, HG | 1 |
| Wells, A | 1 |
4 other studies available for pd 153035 and Adenocarcinoma
| Article | Year |
|---|---|
Leptin stimulates the proliferation of human oesophageal adenocarcinoma cells via HB-EGF and Tgfalpha mediated transactivation of the epidermal growth factor receptor.
Topics: Adenocarcinoma; Amphiregulin; Autoantibodies; Cell Line, Tumor; Cell Proliferation; EGF Family of Pr | 2008 |
Antitumor activity of a novel EGFR tyrosine kinase inhibitor against human lung carcinoma in vitro and in vivo.
Topics: Adenocarcinoma; Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, | 2009 |
PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Enzyme Inhibitors; Er | 1997 |
A role for phospholipase C-gamma-mediated signaling in tumor cell invasion.
Topics: Adenocarcinoma; Animals; Autocrine Communication; Breast Neoplasms; Cell Line; Diffusion Chambers, C | 1999 |